Example sentences for: crosslinking

How can you use “crosslinking” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Because our integrin-CD98 complex was observed in light membrane fractions and not in dense sucrose gradient fractions, and because we could not capture the complex by covalent crosslinking (not shown), the interaction may not be direct.

  • We examined the effect of incubation time and temperature during fixation with 4% PFA in PBS(+), since conditions for irreversible crosslinking of polypeptides in cultured cells with formaldehyde are unknown.

  • Fractionation by SDS-polyacrylamide gel electrophoresis and autoradiography of the resulting immunocomplexes from these cells showed crosslinking exclusively to HA-Smo, but with an efficiency of less than 1% (data not shown).

  • Although several laboratories reported that crosslinking CD5 on the surface augments T cells signaling by inducing calcium flux and enhancing mitogenic response [ 14, 15, 16], recent studies using CD5-deficient mice indicate that CD5 may be more important as a negative modulator of TCR and BCR signal transduction [ 17, 18].

  • When suitable anti-light chain reagents become available, this could be directly tested in covalent crosslinking experiments.


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