Example sentences for: crosslinking

How can you use “crosslinking” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We have recently demonstrated that Rlk is phosphorylated following stimulation of the Jurkat T cell line by crosslinking of the CD3ε chain of the TCR [ 19].

  • Btk kinase activity and tyrosine phosphorylation increase upon stimulation of sIgM as well as the IL-5 and IL6 receptors in B cells, and upon crosslinking of the high affinity IgE receptor (FcεRII) in mast cells [ 12, 13, 14, 15].

  • We incubated this compound at 0.5 μM with HA-Smo- or control, GFP-transfected 293T cells and subsequently ultraviolet-irradiated them to initiate crosslinking.

  • We used Lymphochip microarrays to profile the changes in gene expression that occurred in response to a wide variety of signaling events: B-cell lymphoma cell lines stimulated by crosslinking the B-cell antigen receptor or by treatment with phorbol ester and ionomycin (PI), resting peripheral blood T cells stimulated with PI, and peripheral blood monocytes stimulated with lipopolysaccharide.

  • By crosslinking protein sulfhydryl groups, diamide is thought to disrupt protein structure and trigger oxidative stress [ 57, 58], both of which are likely to perturb normal ER functions [ 59].


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