Example sentences for: couplers

How can you use “couplers” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • As a receptor class, GPCRs are considered excellent drug targets because they are often regulated through interactions with small natural ligands [ 32 33 ] . Specifically, studies of classic GPCRs, such as the β-adrenergic receptors, show that in the absence of endogenous ligand (agonists) these receptors exist in multiple interconvertible conformations that are predominately inactive [ 34 ] . Upon exposure to their natural ligands, however, the active receptor forms are preferentially stabilized, allowing them to readily engage G-protein couplers and to create signaling-competent complexes.


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