Words similar to coupler
Example sentences for: coupler
How can you use “coupler” in a sentence? Here are some example sentences to help you improve your vocabulary:
Briefly, if this model is applied to Hh signaling, it proposes that, firstly, agonist and antagonists act at independent sites to select active and inactive conformations of Smo; secondly, that Smo engages an undefined coupler/effector, when it is in its signaling state; and finally, that the gain-of-function mutant form of Smo, Smo act, adopts an abnormal conformation that resembles the coupler/effector-bound signaling state of Smo with low affinity for antagonists but normal affinity for the agonist.
The model further suggests that the Smo actprotein resides in a stable conformation in the absence of agonist that is capable of forming an active coupler/effector complex resistant to antagonist, but not agonist, binding.
Throughout the discussion the term 'coupler/effector' is used to describe an unknown molecule that binds activated Smo in such a way as to trigger signal transduction.
Tests on other locations of the dipole relative to the phantom (near the ear, the loop or the meander) showed no influence up to a maximum available radiation power of 6 W. The uncertainty of the transmitting power measurement was less than ± 30%, and is basically composed of the uncertainty of the power measurement itself and the uncertainty of the direction coupler parameters.
Thus, in considering models of Ptc function based on Hh-stimulated effects it is important to consider whether the form of Smo that is being observed is the active (coupler/effector bound) signaling state, or perhaps a downregulated and inactive form.
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