Words similar to coupled
Example sentences for: coupled
How can you use “coupled” in a sentence? Here are some example sentences to help you improve your vocabulary:
§§ 603(b)(1) and (2), the analysis, coupled with the summary in the preamble, explains the reasons and objectives, as well as legal bases, for the proposed rule.
Measurements of mRNA and protein made in many laboratories using diverse methodologies have identified approximately 40 genes that are up-regulated and 25 down-regulated after peripheral nerve injury [ 3 5 6 ] . These regulated genes include members of several classes: G protein coupled receptors, ligand- and voltage-gated ion channels, receptor tyrosine kinases, growth factors, cytokines, neuropeptides, cell cytoskeletal genes, cell surface/extracellular matrix genes, and a miscellaneous group of enzymes.
Immunoprecipitations from the transfected cell lysates were performed with anti-FLAG antibody coupled Agarose beads (Sigma) and then the beads were washed six times in the lysis buffer.
Because the use of CAM has become more prevalent in the general population in recent years, coupled with the fact that 70% of all pregnant women suffer from NVP, one might be able to extrapolate these results to the general population of women who suffer from NVP, but did not call the NVP helpline.
Prostaglandin E 2 is a major cyclooxygenase metabolite of arachidonic acid which exerts diverse effects on vascular smooth muscle tone and epithelial solute transport via G-protein coupled receptors [ 1 2 ] . At least four distinct G-protein coupled PGE 2 receptors have been cloned: the EP 1 , EP 2 , EP 3 , and EP 4 [ 1 ] . Pharmacological studies suggest PGE 2 relaxes vascular smooth muscle through two of these receptors, the EP 2 and EP 4 receptors, which couple to cyclic-AMP generation [ 3 ] . In contrast, PGE 2 constricts other vascular smooth muscle through EP 3 receptors which inhibit cAMP generation via G i or EP 1 receptors which increase Ca 2+mobilization [ 3 ] . Although both EP 2 and EP 4 receptors relax smooth muscle, EP 2 receptors are uniquely sensitive to the agonists butaprost and AH13205 [ 3 4 ] . Previous studies have shown that PGE 2 increases the cAMP concentration in many tissues including kidney, intestine and uterus, but the relative contribution of EP 2 versus EP 4 receptors to these effects is incompletely defined [ 5 6 ] . Recent studies in mice with targeted disruption of these receptors have suggested an important role for EP2 receptor in regulating systemic hemodynamics.
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