Words similar to constitutively

Example sentences for: constitutively

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A portion of the cellular eIF4E is imported into the nucleus through a mechanism that requires the protein 4E-T [ 31 ] . In the nucleus eIF4E is localized to specific nuclear bodies and associates with promyelocytic leukemia protein (PML, [ 32 ] ). Nuclear eIF4E appears to be involved in export of cyclin D1 mRNA to the cytosol [ 25 ] . Both 4E-T and PML interact with the same domain of eIF4E that binds 4EBP [ 32 ] . Thus expression of constitutively active 4EBP may block nuclear functions of eIF4E, one consequence being a reduction in cyclin D1 mRNA that can be translated in the cytoplasm.
In static cell adhesion assays, however, Rho activity is not required to maintain constitutively high levels of adhesion to fibronectin.
Cotransfection of a plasmid expressing a constitutively active mutant Stat3, Stat3C, that forms homodimers and translocates to the nucleus without tyrosine phosphorylation, affected AR transcriptional activity in a dose-response manner (Fig.
Constitutively activated Stat3 also activates another androgen-responsive reporter contained the fragment -286/+28 of the rat Probasin (PB) promoter (Fig.
To verify equal protein loading membranes were then stripped and re-probed with the panERK antibody (1:1000; Transduction Laboratories; Lexington, KY) which recognizes the constitutively expressed ERKs in bovine CLENDO cells as previously described [ 35 ] .