Words similar to collagen-induced
Example sentences for: collagen-induced
How can you use “collagen-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:
Moreover, induction of Th2 cells in a Th1-mediated disease model of collagen-induced arthritis led to amelioration of autoimmune disease [ 16].
Tumor necrosis factor alpha (TNF-α) is elevated in sera and synovial fluid of patients with RA, suggesting that it may play a role in the pathology of the disease [ 4 ] . Soluble TNF-α receptor or neutralizing antibodies against TNF-α have been shown to prevent collagen-induced arthritis in mice [ 5 6 ] . Furthermore, a human TNF-α (hTNF-α) transgenic mouse (Tg197) develops a chronic, progressive polyarthritis with histologic features in common with RA [ 7 ] . Weight loss and joint swelling in these mice are correlated with expression of hTNF-α mRNA in the joints [ 7 ] and hTNF-α concentrations in the serum [ 8 9 ] . Previously, Keffer et al.
In addition, TGF-β1 has been shown to be therapeutic in murine models of collagen-induced arthritis following delivery in genetically modified T cells [ 28 ] . This observation suggests that targeting TGF-β1 to certain sites of inflammation through the use of arthogenic T cells also can be therapeutic.
CIA = collagen-induced arthritis; ELISA = enzyme-linked immunosorbent assay; Th = T helper; PG = proteoglycan; IFN = interferon; IL = interleukin; SEM = standard error of the mean.
CFA = complete Freund's adjuvant; CIA = collagen-induced arthritis; ELISA = enzyme-linked immunosorbent assay; FACS = fluorescence-activated cell sorting; FITC = fluorescein isothiocyanate; H & E = hematoxylin and eosin; IFN = interferon; IL = interleukin; MHC = major histocompatibility complex; PCR = polymerase chain reaction; Th cells = T helper cells; TNF-α = tumor necrosis factor alpha; WT = DBA/1 wildtype.
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