Words similar to collagen-induced
Example sentences for: collagen-induced
How can you use “collagen-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:
In animal models of arthritis, systemic treatment with IL-10 and adenovirus-mediated transfer of viral IL-10 moderately suppresses the development of arthritis, but is significantly more effective when combined with IL-4 [ 19 20 21 22 23 24 ] . The evidence for the importance of IL-10 is further supported by the fact that in vivo anti-IL-10 treatment accelerates disease in collagen-induced arthritis (CIA) [ 22 ] .
Siemann and Creasy proposed that trans-resveratrol, a tri-hydroxy stilbene, in red wine exhibits cardioprotective properties [ 18] and can inhibit LDL oxidation [ 19], suppress smooth muscle proliferation [ 20], induce nitric oxide synthase expression [ 21] and block collagen-induced aggregation responses in washed platelets [ 22, 23, 24].
CIA = collagen-induced arthritis; ELISA = enzyme-linked immunosorbent assay; Th = T helper; PG = proteoglycan; IFN = interferon; IL = interleukin; SEM = standard error of the mean.
Moreover, anti-TNF-α treatment resulted in a modest inhibition of murine IL-1β production in the diseased joint, which is consistent with previous findings that anti-TNF-α antibody inhibits the generation of IL-1 in collagen-induced arthritis and IL-1, IL-6, and IL-8 in rheumatoid synovial cultures [ 26 27 ] . Our study provides preclinical evidence supporting the use of anti-TNF-α mAb in ameliorating arthritic pathology.
In addition, TGF-β1 has been shown to be therapeutic in murine models of collagen-induced arthritis following delivery in genetically modified T cells [ 28 ] . This observation suggests that targeting TGF-β1 to certain sites of inflammation through the use of arthogenic T cells also can be therapeutic.
Loading...