Example sentences for: collagen-induced

How can you use “collagen-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • CIA = collagen-induced arthritis; ELISA = enzyme-linked immunosorbent assay; Th = T helper; PG = proteoglycan; IFN = interferon; IL = interleukin; SEM = standard error of the mean.

  • Paradoxically, in collagen-induced arthritis (CIA), disease is suppressed in IL-4-deficient mice [ 28].

  • CFA = complete Freund's adjuvant; CIA = collagen-induced arthritis; ELISA = enzyme-linked immunosorbent assay; FACS = fluorescence-activated cell sorting; FITC = fluorescein isothiocyanate; H & E = hematoxylin and eosin; IFN = interferon; IL = interleukin; MHC = major histocompatibility complex; PCR = polymerase chain reaction; Th cells = T helper cells; TNF-α = tumor necrosis factor alpha; WT = DBA/1 wildtype.

  • In animal models of arthritis, systemic treatment with IL-10 and adenovirus-mediated transfer of viral IL-10 moderately suppresses the development of arthritis, but is significantly more effective when combined with IL-4 [ 19 20 21 22 23 24 ] . The evidence for the importance of IL-10 is further supported by the fact that in vivo anti-IL-10 treatment accelerates disease in collagen-induced arthritis (CIA) [ 22 ] .

  • In addition, TGF-β1 has been shown to be therapeutic in murine models of collagen-induced arthritis following delivery in genetically modified T cells [ 28 ] . This observation suggests that targeting TGF-β1 to certain sites of inflammation through the use of arthogenic T cells also can be therapeutic.


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