Words similar to collagen-induced
Example sentences for: collagen-induced
How can you use “collagen-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:
In addition, TGF-β1 has been shown to be therapeutic in murine models of collagen-induced arthritis following delivery in genetically modified T cells [ 28 ] . This observation suggests that targeting TGF-β1 to certain sites of inflammation through the use of arthogenic T cells also can be therapeutic.
Tumor necrosis factor alpha (TNF-α) is elevated in sera and synovial fluid of patients with RA, suggesting that it may play a role in the pathology of the disease [ 4 ] . Soluble TNF-α receptor or neutralizing antibodies against TNF-α have been shown to prevent collagen-induced arthritis in mice [ 5 6 ] . Furthermore, a human TNF-α (hTNF-α) transgenic mouse (Tg197) develops a chronic, progressive polyarthritis with histologic features in common with RA [ 7 ] . Weight loss and joint swelling in these mice are correlated with expression of hTNF-α mRNA in the joints [ 7 ] and hTNF-α concentrations in the serum [ 8 9 ] . Previously, Keffer et al.
Siemann and Creasy proposed that trans-resveratrol, a tri-hydroxy stilbene, in red wine exhibits cardioprotective properties [ 18] and can inhibit LDL oxidation [ 19], suppress smooth muscle proliferation [ 20], induce nitric oxide synthase expression [ 21] and block collagen-induced aggregation responses in washed platelets [ 22, 23, 24].
Blocking the effect of RANTES has, however, also been shown to be effective in ameliorating collagen-induced arthritis in DAB/1 mice and adjuvant-induced arthritis in rats [ 24, 25].
Under these conditions IL-1Ra has both antierosive and anti-inflammatory effects in collagen-induced arthritis.
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