Words similar to collagen
Example sentences for: collagen
How can you use “collagen” in a sentence? Here are some example sentences to help you improve your vocabulary:
The drug inhibited COL1A2 steady-state mRNA levels and promoter activity by 60%, indicating that it directly inhibits transcription of this collagen gene.
The altered adhesion of IDO-expressing RAW cells to collagen suggested that IDO might induce alterations in enzymes involved in modifying the extracellular matrix.
Given the broad spectrum of IL-1-induced enzymes, we consider that regions of the tissue where [GAG] is more severely affected by IL-1 may also be regions that experience greater damage to the collagen network, as compared with regions that are more resistant to the effects of IL-1.
When the tissue temperature drops to below 40°C, these bonds can reunite with possible rearrangement of the matrix but without any cellular damage [ 16 ] . Under this consideration the thermal contact of the 49°C preheated PALM gel onto the bare corneal stroma for the in situ molding of the lenticule, would not be expected to induce any irreversible changes of the corneal collagen chains.
The notion that the differential ability to replenish GAG fully is related to the differential state of the collagen matrix has been suggested by others, based in part on the finding that GAG depletion corresponds with regions that are positive for the col3/4 epitope, which is indicative of collagen damage [ 6 26 ] . Although we lack specific information on the state of the collagen matrix, the differences observed in the present study (and, indeed, the demonstrated ability to evaluate regional differences in response) suggest that dGEMRIC and model systems such as these may be useful for establishing a better understanding of the capacity of cartilage to repair osteoarthritis-like degradation.
Loading...