Example sentences for: collagen

How can you use “collagen” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the absence of SPARC, expression of transforming growth factor-β1 and type I collagen is down-regulated in kidney mesangial cells [ 15 ] . The expression of cell surface receptor for insulin-like growth factor I in SPARC-null embryonic fibroblasts is also diminished [ 16 ] . Studies with SPARC-null cells have confirmed that SPARC functions in cell proliferation.

  • Binding of GPIa/IIa to collagen induces a conformational change in receptor structure that enhances affinity.

  • Laminin is a glycoprotein composed of three chains, A, B1, and B2 in a cross-shaped molecule; this protein is found in basement membranes where it interacts with other such components as collagen IV, heparan-sulfate proteoglycan, and nidogen [ 45 ] . Laminin contains EGF-like modules in the amino-terminal region of the A, B1, and B2 chains [ 45 ] . Surprisingly, these modules do not appear to be involved in the binding of fibulin-1.

  • Serum level of antibody against type II collagen was measured using a standard ELISA assay.

  • In conclusion, our study shows that CPT has a potent selective inhibitory effect on collagen gene expression; however, the specific molecular mechanisms of action are presently not known and will require further study.


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