Example sentences for: coagulation

How can you use “coagulation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Incubation with combined PN-1 and uPA resulted in rapid coagulation as in control.

  • TSP-1 is a homotrimeric multidomain glycoprotein synthesized and secreted by numerous cell types, including platelets, vascular smooth muscle cells and keratinocytes [ 4 ] . Due to its interaction with a wide variety of proteins, TSP-1 has been implicated in a number of biological processes including coagulation, cell adhesion, the modulation of cell-cell and cell-matrix interactions, control of tumor growth and metastasis, and angiogenesis [ 10 ] . Inhibition of tumor cell proliferation has been achieved in vivo by systemic treatment with TSP-1 peptide mimetics [ 11 ] , but a correlation between primary tumor TSP-1 expression and poor prognosis has not been clearly established [ 12 ] . While there are reports that these molecules can originate from tumor cells [ 13 ] , the majority of reports have suggested that the major source of both TSP-1 and OPN is tumor-associated stroma [ 14 ] or infiltrating macrophages and lymphocytes [ 15 ] .

  • The EGF domain, which often occurs as multiple tandem repeats, is widely distributed among extracellular proteins involved in adhesion, receptor-ligand interactions, extracellular matrix structure, determination of cell fate, and blood coagulation [ 27 ] . Cell adhesion usually activates PI 3-kinase activity.

  • Substantial tolerance of one or two nucleotide mismatch in siRNA-mediated silencing of human coagulation trigger tissue factor mRNA has been reported recently [ 46 ] . When siRNA transfected cells were infected with RSV, the virus was added 10 hours after transfection.

  • For example, because about 80% of strokes are caused by thrombotic occlusion of a blood vessel, genes related to the coagulation system would seem logical candidates for susceptibility to stroke.


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