Words similar to coactivators

Example sentences for: coactivators

How can you use “coactivators” in a sentence? Here are some example sentences to help you improve your vocabulary:

Several possible mechanisms have been suggested to explain this activation of AR, including mutations in the gene encoding AR that alter the specificity for androgens, overexpression of the AR protein itself, cross-talk to other signal transduction pathways, and altered levels or activity of coactivators [ 21 22 23 ] . Several groups including ours have demonstrated a role of activated Stat3 in the proliferation and survival of prostate cancer cells by a mechanism that involves the AR [ 24 25 26 27 28 ] .
3shows, coexpression of active Stat3C simultaneously to SRC-1, CBP/p300, TIF-2 or P/CAF, resulted in a more efficient enhancement of the reporter transcription activity driven by AR as compared with any of the coactivators expressed separately.
This interaction may be direct, or it may occur indirectly through the action of coactivators, which act as bridging factors.
Together, our results indicate that ERβ has the potential to utilize its AF-2 surface to bind NR boxes within coactivators or an NR box-like sequence in the C-terminus of N-CoR.
Here we show that constitutively active Stat3 enhances transcriptional activity of SHRs, AR, GR, PR, and ER, in a comparable extent to the stimulation elicit by other coactivators, and even more, in a synergistic manner to these other coactivators.