Words similar to coactivators

Example sentences for: coactivators

How can you use “coactivators” in a sentence? Here are some example sentences to help you improve your vocabulary:

In the case of the PPARγ/RXR complex, for example, activation with PPAR or RXR specific ligands results in recruitment of quite different coactivators [ 19 ] .
Here we show that constitutively active Stat3 enhances transcriptional activity of SHRs, AR, GR, PR, and ER, in a comparable extent to the stimulation elicit by other coactivators, and even more, in a synergistic manner to these other coactivators.
In experiments studying synergy of coactivators, the total amount of DNA was kept constant at 4.4 μg per well.
The nuclear receptor (NR) family comprises 48 structurally related transcription factors, many of which require their cognate ligand for activity [ 1 2 3 ] . The NRs regulate transcription by binding to response elements in the promoters of target genes and acting as scaffolds for the assembly of large coactivator and corepressor complexes [ 4 ] . NR coactivators include the p160s (including GRIP1/TIF-2, SRC-1 and AIB1/ACTR/pCIP).
The recent findings that members of the several different families of coactivators possess intrinsic histone acetyltransferase activity suggests that activated SHRs, and nuclear receptors in general, may also recruit these cofactors to remodel chromatin structure for better accessibility of the transcriptional machinery to DNA [ 5 6 ] .