Example sentences for: coactivators

How can you use “coactivators” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • [ 18 ] . This constitutively activated Stat3 (a mutant produced by substitution of the cysteine residues within the COOH-terminal loop of the SH2 domain of Stat3) induces cellular transformation and tumor formation in nude mice [ 18 ] . The plasmids to express other coactivators (SRC-1, CBP/p300, TIF2 and PCAF) have been described elsewhere [ 29 30 ] .

  • We determined whether Stat3 could act in a synergistic/additive way when administered to cells simultaneously to other coactivators.

  • Prominent among these coactivators is the SRC (steroid receptor coactivator) family, which consists of SRC-1, TIF2/GRIP1, and RAC3/ACTR/pCIP/AIB-1.

  • There is most likely a large protein complex assembled at the SRE composed of regulated transcription factors, coactivators, and the basal transcriptional machinery, resulting in rapid transcription of the c-fos gene in response to mitogenic stimulation.

  • Accessory cells were effectively removed during T cell isolation as shown by the failure of mitogen-induced proliferation in the absence of coactivators.


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