Example sentences for: coactivators

How can you use “coactivators” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • More complex combinatorial effects of other coactivators or corepressors (e.g.

  • Prominent among these coactivators is the SRC (steroid receptor coactivator) family, which consists of SRC-1, TIF2/GRIP1, and RAC3/ACTR/pCIP/AIB-1.

  • This interaction may be direct, or it may occur indirectly through the action of coactivators, which act as bridging factors.

  • Other NR coactivators include TRAP220 [ 7 ] , which is part of a larger complex (TRAP/DRIP/SMCC/mediator) that contacts the basal transcription machinery and PGC-1 [ 8 ] , a cold inducible coactivator that binds CBP and SRC-1 and proteins involved in RNA processing [ 9 ] . NR corepressors include NR corepressor (N-CoR) and silencing mediator of retinoid and thyroid responsive transcription (SMRT) [ 4 ] . Both N-CoR and SMRT repress transcription, at least in part, by binding to histone de-acetylases (HDACs) either directly or indirectly through other corepressor complex components.

  • Coactivators are probably present in the nucleus in preassembled multicomplex units ready to associate to activated SHRs.


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