Words similar to coactivator

Example sentences for: coactivator

How can you use “coactivator” in a sentence? Here are some example sentences to help you improve your vocabulary:

Recently, overexpression of SRC-1 and TIF-2 has been found in prostate cancer recurrence after androgen deprivation therapy [ 44 ] , providing a molecular basis for AR activation that could be similar to the one displayed by Stat3 in its role as coactivator.
As expected, 9-cis-RA stimulated coactivator binding to RXR alone, and the basal interaction of CAR with SRC-3 was enhanced by TCPOBOP and decreased by androstanol (Fig.
Decreased growth factor and growth factor receptor expression has been proposed as a potential growth inhibitory mechanism [ 14 ] . Additionally, RA mediated inhibition of AP-1 activity is believed to be important in cellular growth control by this ligand [ 13 ] . AP-1 inhibition via direct interaction between RARs and AP-1 proteins has been proposed [ 16 ] . RA inhibition of jun N-terminal kinase was shown to prevent c-jun phosphorylation, resulting in decreased AP-1 activity [ 17 ] . Competition between RAR and AP-1 for limiting amounts of the nuclear receptor coactivator CBP may also account for decreases in AP-1 transcriptional activity [ 5 ] . In the present study we have described a new mechanism by which RA can inhibit cellular proliferation.
PERC PGC-1 related estrogen receptor coactivator
We studied whether Stat3, a transcription factor itself, could act as a coactivator for AR and for other SHRs.