Words similar to chromatin
Example sentences for: chromatin
How can you use “chromatin” in a sentence? Here are some example sentences to help you improve your vocabulary:
As specialized proteins of the intermediate filament protein family, lamin A/C is found at the inner nuclear membrane where it forms a scaffold that interacts with a network of membrane bound and nucleoplasmic proteins in addition to chromatin [ 3 4 5 ] . Mutations in the gene encoding the nuclear membrane protein emerin produce autosomal recessive Emery Dreifuss Muscular Dystrophy, a disorder that phenotypically overlaps the neuromuscular and cardiovascular features seen with lamin A/C mutations [ 6 ] . Consistent with this, lamin A/C directly binds emerin [ 7 8 ] . Lamins A and C are broadly expressed in many different cell types and are primarily expressed in terminally differentiated cells.
We observed that C/EBPα, expressed in mouse pituitary progenitor GHFT1-5 cells, also localized to peri-centromeric chromatin [ 45 ] . Here we show that targeting of C/EBPα to peri-centromeric chromatin in GHFT1-5 cells required the DNA binding domain of C/EBPα (Fig.
These homologous proteins are parts of the multisubunit SWI/SNF and RSC complexes that drive chromatin remodeling through the SNF2/SWI2-like ATPase subunit [ 26, 27, 28].
It is also possible that differences in the chromatin context could contribute to the differences between the effects observed with the endogenous and transiently transfected promoters.
It will be important in future work to refine these results and test, for example, whether NPM3 may have chromatin or ribosome assembly functions that are similar or complementary to nucleoplasmin or nucleophosmin, or whether it may have completely independent functions.
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