Words similar to cho-mk

Example sentences for: cho-mk

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As expected, autophosphorylation of the IGF-IRs was observed in the CHO and CHO-WT cells but very little was seen in two different clones of CHO-MK cells, indicating that the kinase-defective receptors inhibited the endogenous wild-type hamster receptors (Figure 1A).
The ability of the CHO-MK cells to incorporate thymidine in response to IGF-I is markedly diminished as compared to the parental cell line (Figure 1B).
To confirm that the kinase-defective receptors were functioning in a dominant-negative fashion, we studied the ability of CHO and CHO-MK cells to incorporate 3H-thymidine into DNA in response to IGF-I stimulation.
Not only did we observe a difference of the number of colonies, but CHO-MK colonies were smaller than either the parental CHO or CHO-WT colonies (data not shown).
Very few apoptotic cells are seen in the CHO parental and CHO-WT cells, whereas apoptotic cells are seen throughout the tumor from the kinase-defective CHO-MK cells.