Example sentences for: chaperones

How can you use “chaperones” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Members of the HSP70 family have also been proposed to be involved with HSP90 chaperones regulating signal transduction pathways [ 32 ] . Unlike HSP70, HSC70 does not exhibit increased gene expression when exposed to heat stress or other agents such as sodium arsenate in the gastrula and neurula Xenopus embryo [ 33 ] . Tsang [ 34 ] suggested because of their ability to bind and transport folded and un-folded cellular proteins, HSP70 family members may function as a cross-linker to couple cellular proteins to the cytoskeletal matrix.

  • Molecular chaperones bind to nascent proteins in the endoplasmic reticulum (ER), promote proper protein folding, and prevent the aggregation of nonnative and misfolded proteins.

  • Another preliminary finding of this study is that several molecular chaperones appear to be localized to the egg surface.

  • These include proteases in thermophilic bacteria, transcription factors, and chaperones that promote protein refolding.

  • Compromised ER function (induced by numerous stressors including depletion of ER calcium stores) may lead to the accumulation of unfolded proteins in the ER [ 11 ] . These events may trigger the UPR, in which the transcription of genes encoding ER-resident chaperones is upregulated.


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