Words similar to chaperone
Example sentences for: chaperone
How can you use “chaperone” in a sentence? Here are some example sentences to help you improve your vocabulary:
The number of examples in this category could be increased, and some have already been considered in the literature, for example the spurious discovery of a 'functional PDZ domain' in the molecular chaperone ClpA ([ 46], see refutation in [ 47]) or the finding of an ATPase domain and death effector domains in the apoptosis-associated protein FLASH ([ 48], see refutation in [ 49]).
The key cellular element that is critical for this process is molecular chaperone Hsp104 (Chernoff et al.
For Hsp33, this structural change allows for dimerization and activates its chaperone activity (Graf et al.
It has been known for over 30 years that vitamin D status influences the level of calbindin D, a cytosolic calcium-binding protein [ 6 ] believed to be the rate-limiting step in calcium absorption [ 7 ] by acting as an intracellular calcium ferry or chaperone.
The coordinated vitamin D-dependent induction of the cytosolic calcium-binding protein calbindin D could serve this function when the need for transcellular calcium flux is high by acting directly or indirectly as a molecular sponge and selectively removing calcium ions from the CaT1 channel and/or to buffer increases in intracellular calcium, thereby preventing premature inactivation of this I CRAC channel [ 15 ] . Calbindin D could also play its traditionally conceived role as a calcium chaperone protein to facilitate the transfer of calcium through the cytosol [ 32 ] and perhaps delivery of Ca ++to the basolateral ATP-dependent calcium pump for extrusion out of the enterocyte [ 33 ] .
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