Words similar to chaperone
Example sentences for: chaperone
How can you use “chaperone” in a sentence? Here are some example sentences to help you improve your vocabulary:
TPR domains consist of a series of antiparallel amphipathic α helices that bundle together through hydrophobic interactions to form a cradle-shaped groove, postulated to be involved in binding a number of proteins of regulatory importance such as heat shock protein 90, a major cellular chaperone [ 8 9 10 ] .
The key cellular element that is critical for this process is molecular chaperone Hsp104 (Chernoff et al.
Based on the serial endosymbiosis theory, the first symbiotic event involved a spirochete [ 3 ] . On the other hand, sequence signatures of the heat shock molecular chaperone protein HSP-70 and other evidence have indicated that the first symbiotic event involved a gram-negative eubacterium [ 6 ] . Our data are unable to distinguish between these two alternatives but agree with both in implicating an earlier, premitochondrial event.
Cdc37 encodes a 50-kDa protein that targets intrinsically unstable oncoprotein kinases including Cdk4, Raf-1, and v-src to the molecular chaperone Hsp90, an interaction that is thought to be important for the establishment of signaling pathways.
The coordinated vitamin D-dependent induction of the cytosolic calcium-binding protein calbindin D could serve this function when the need for transcellular calcium flux is high by acting directly or indirectly as a molecular sponge and selectively removing calcium ions from the CaT1 channel and/or to buffer increases in intracellular calcium, thereby preventing premature inactivation of this I CRAC channel [ 15 ] . Calbindin D could also play its traditionally conceived role as a calcium chaperone protein to facilitate the transfer of calcium through the cytosol [ 32 ] and perhaps delivery of Ca ++to the basolateral ATP-dependent calcium pump for extrusion out of the enterocyte [ 33 ] .
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