Example sentences for: chaperone

How can you use “chaperone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The apparently ubiquitous expression and abundant levels of NPM3 RNA are consistent with other members of this gene family and with a proposed role as a molecular chaperone.

  • Since this chaperone can directly bind to protein aggregates and promote there disassembly (Glover and Lindquist 1998), it was suggested that the main function of Hsp104 in prion inheritance is to disaggregate large prion aggregates to smaller elements, thus leading to formation of new seeds (Kushnirov and Ter-Avanesyan 1998).

  • The N-terminal core region of high similarity between family members correlates to a region in nucleophosmin/B23 that has been shown to be involved in oligomerization as well as chaperone activity [ 44 ] . A central portion between nucleophosmin's two acidic domains is required for ribonuclease activity [ 44 ] ; this region does not have a corresponding domain in either NPM3 or nucleoplasmin, suggesting that these proteins would lack such activity.

  • chaperone protein Hsp33 (Jakob et al.

  • For Hsp33, this structural change allows for dimerization and activates its chaperone activity (Graf et al.


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