Words similar to chaperone
Example sentences for: chaperone
How can you use “chaperone” in a sentence? Here are some example sentences to help you improve your vocabulary:
Substoichiometric amounts of midasin have also been detected in isolated preparations of 60S preribosomal particles suggesting that it may play a role in maturation of 60S ribosome subunits [ 2 ] . Such a role for midasin as a nuclear chaperone involved in the assembly/disassembly of macromolecular complexes in the nucleus would be consistent with our localization data and with the known functions of other AAA proteins.
The coordinated vitamin D-dependent induction of the cytosolic calcium-binding protein calbindin D could serve this function when the need for transcellular calcium flux is high by acting directly or indirectly as a molecular sponge and selectively removing calcium ions from the CaT1 channel and/or to buffer increases in intracellular calcium, thereby preventing premature inactivation of this I CRAC channel [ 15 ] . Calbindin D could also play its traditionally conceived role as a calcium chaperone protein to facilitate the transfer of calcium through the cytosol [ 32 ] and perhaps delivery of Ca ++to the basolateral ATP-dependent calcium pump for extrusion out of the enterocyte [ 33 ] .
However, unlike most of the genes in cluster 58, KAR2 is also induced in response to heat shock, along with the other chaperone genes in cluster 11, by the transcription factor Hsf1p [ 31].
The key cellular element that is critical for this process is molecular chaperone Hsp104 (Chernoff et al.
The highly conserved structure of midasin in eukaryotes, taken in conjunction with its nuclear localization in yeast, suggests that midasin may function as a nuclear chaperone and be involved in the assembly/disassembly of macromolecular complexes in the nucleus.
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