Words similar to ccaf
Example sentences for: ccaf
How can you use “ccaf” in a sentence? Here are some example sentences to help you improve your vocabulary:
These findings suggest that during wound healing, cCAF produced by the resident fibroblasts chemoattracts additional fibroblasts that contribute to the production of these ECM molecules, which then support migration of both fibroblasts and other cells in the wound tissue.
TN and FN, especially in combination, promote migration, therefore cCAF may facilitate fibroblast migration by increasing TN and FN levels.
We show that: (i) cCAF stimulates TN expression and that a 15 aa peptide containing the N-terminal sequence causes the same effects as the whole molecule; (ii) in contrast to its effects on TN production, cCAF-induced increase in FN and Coll I accumulation requires the whole molecule; (iii) the increase in FN protein is not a result of a corresponding increase in mRNA, or increase in MMP production or PA activity but appears to be linked TN production; (iv) increase in Coll I correlates with decreased levels of MMP-1; (v) cCAF chemoattracts fibroblasts and accelerates their migration; (vi) treatment of excision wounds with cCAF increased the levels of all three ECM molecules in the granulation tissue of wounds albeit with different dynamics.
To investigate whether activity of PA might be decreased with cCAF treatment leading to accumulation of FN, we examined the levels of PA activity.
This dose of cCAF was chosen because it was the optimal dose for inducing differentiation of myofibroblasts, cells known to produce large amounts of ECM [ 4 ] . Media was changed and new cCAF or peptides added every day for 4 days.
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