Words similar to ccaat

Example sentences for: ccaat

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To determine which of these potential transcription factor binding sites is responsible for regulating normal CD5 expression, we performed site-directed mutagenesis on the CCAAT (mutC), κE2 (mutK) and Ets (mutE) sites from the StuI B reporter construct.
Electrophoretic patterns with a probe corresponding to the DQA1*0501 Y-box sequence, which diverges from the DQA1*0101 Y-box sequence by a single base pair within the highly conserved reverse CCAAT sequence, appear to vary with the cell type, and binding appears weaker than with the DQA1*0101 probe (see Fig.
As figure 2shows, mutations in the CCAAT or κE2 binding site resulted in minor reductions in reporter activity.
The consensus ( HLA-DRA ) Y-box sequence differs from the HLA-DQA1*0101 Y box by a single nucleotide immediately 5' of the reverse CCAAT pentamer; this single-nucleotide polymorphism significantly changes the electrophoretic pattern (Fig.
Consistent protection is also seen at position 2, adjacent to the A-for-G substitution that diverges from the Y-box consensus sequence, although there is no protection of the divergent base itself at position 3. DNase I protection by recombinant DEK extends over the length of the Y-box sequence, including bases within the NF-Y binding site (reverse CCAAT sequence), again suggesting that the two proteins may interact.