Words similar to ccaat

Example sentences for: ccaat

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The CK oligo contains CD5 κE2 and CCAAT sites.
In some differentiating cell types, changes in both gene transcription and proliferation are regulated by the same transcription factor [ 1 2 3 4 5 6 7 8 9 ] . CCAAT/Enhancer Binding Protein alpha (C/EBPα) is a transcription factor that is required for the differentiation of a number of tissues [ 10 11 12 13 14 15 16 17 18 ] . Mice homozygous for C/EBPα null alleles have severe defects in tissues involved in metabolic homeostasis [ 19 20 21 ] . Cellular proliferation is elevated in the liver of these knockout mice [ 22 ] suggesting that C/EBPα blocks proliferation in vivo.
The mutagenesis primers corresponding to each of the five regions, Ets (mutE), κE2 (mutK), CCAAT (mutC), CD5X (Xmut1, 2, and 3), and CD5Y (Ymut1 and 2) were synthesized at the Protein and Nucleic Acid Facility, Stanford University.
Consistent protection is also seen at position 2, adjacent to the A-for-G substitution that diverges from the Y-box consensus sequence, although there is no protection of the divergent base itself at position 3. DNase I protection by recombinant DEK extends over the length of the Y-box sequence, including bases within the NF-Y binding site (reverse CCAAT sequence), again suggesting that the two proteins may interact.
In the liver, cAMP regulates Pck1 transcription via the binding of CREB, as well as CCAAT/enhancer binding protein (C/EBP), to the CRU.