Example sentences for: cbl

How can you use “cbl” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The first CBL/SOS3 was isolated as a protein involved in salt stress (SOS3) and as a calcineurin B-like protein (CBL1) [ 23, 24].

  • CBL/SOS3S show similarity to the B subunit (Figure 2).

  • CBL/SOS3S fall into group III (Figure 6).

  • BCR-induced interaction between Cbl and Syk increases the susceptibility of Syk to proteolysis [ 55 ] , possibly through enhancement of ubiquitination [ 56 ] . Expression of a dominant-negative SHP-1 phosphatase in the mature murine B cell line K46 resulted in an increase in BCR-induced Syk kinase activity as measured by C3b phosphorylation in an ICKA and enhanced BCR-induced Ca 2+fluxes [ 57 ] . It remains to be determined if interference with any of these known regulatory proteins is responsible for the dominant-positive effect.

  • The dependence of this increased turnover on phosphorylation of Rlk suggests that a phosphotyrosine-dependent association with another molecule may be required for this process, reminiscent of the increased degradation of the PDGF receptor and Syk caused by association with the ring-finger protein Cbl [ 47, 48, 49] or the Lck-dependent degradation of the TCR [ 50].


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