Words similar to carbenoxolone

Example sentences for: carbenoxolone

How can you use “carbenoxolone” in a sentence? Here are some example sentences to help you improve your vocabulary:

Carbenoxolone at doses 100, 200 and 300 mg/kg and diazepam at the dose of 1 mg/kg and normal saline (10 ml/kg) were injected interaperitonially to separate groups.
Present results indicate that carbenoxolone has anticonvulsant activities in PTZ and MES models.
It is suggested that carbenoxolone, by blocking GJ channels inhibits both the induction and duration of epilepsy in the in vivo models of seizures.
In the potentiation of pentobarbitone sleep test, carbenoxolone significantly increased the sleeping time in mice at doses of 100, 200 and 300 mg/kg compared to controls dose dependently (Table 3).
In in vitro studies, carbenoxolone abolished the generation of full or partial ectopic spike generation, by 4-AP, in the CA 3 region of rat hippocampal slices [ 6 ] . Also carbenoxolone depresses spontaneous epileptiform activity in the CA 1 region of rat hippocampal slices [ 7 ] . Carbenoxolone appears to cross the blood brain barrier about one hour after an intraperitoneal injection in rats as there was the inhibition of 11-β-hydroxysteroid dehydrogenase in multiple brain regions [ 1 ] . It and/or its congener glycyrrehetinic acid may also enter the eyes of humans.