Example sentences for: carbenoxolone

How can you use “carbenoxolone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 1 h after receiving carbenoxolone and normal saline and 30 min after receiving diazepam, each animal was injected sodium pentobarbitone (30 mg/ kg, i.p).

  • Present results indicate that carbenoxolone has anticonvulsant activities in PTZ and MES models.

  • In the traction test, carbenoxolone did not induce a muscle relaxant activity significantly up to a dose of 400 mg/kg.

  • Less is known about the effects of carbenoxolone on GJs, although it has been proposed that glycyrrhetinic acid, to which carbenoxolone is related, binds directly to connexin molecules causing a conformational change leading to a closure of the junction [ 7 ] . Modeling studies indicate that neuronal synchronization can be mediated by low densities of GJs either between dendrites, as long as these dendrites are excitable [ 10 ] , or between the axons of pyramidal cells [ 11 ] . Furthermore, the electrotonic coupling could be promoted during epileptogenesis [ 12 13 ] .

  • Carbenoxolone (400 mg/kg) showed muscle relaxant activity compared to normal saline, and this effect was more than diazepam in a dose of 0.25 mg/kg (Table 4).


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