Example sentences for: carbenoxolone

How can you use “carbenoxolone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Glycyrrhetinic acid is an aglycone saponin extracted from licorice root [ 7 ] and saponines have hypnotic effects [ 17 ] . Carbenoxolone is also the succinyl ester of glycyrrhetinic acid.

  • Less is known about the effects of carbenoxolone on GJs, although it has been proposed that glycyrrhetinic acid, to which carbenoxolone is related, binds directly to connexin molecules causing a conformational change leading to a closure of the junction [ 7 ] . Modeling studies indicate that neuronal synchronization can be mediated by low densities of GJs either between dendrites, as long as these dendrites are excitable [ 10 ] , or between the axons of pyramidal cells [ 11 ] . Furthermore, the electrotonic coupling could be promoted during epileptogenesis [ 12 13 ] .

  • Present results indicate that carbenoxolone has anticonvulsant activities in PTZ and MES models.

  • Thus, we considered the possible anticonvulsant effect of carbenoxolone in animal seizure models.

  • Diazepam, carbenoxolone and normal saline were injected intraperitoneally (i.p) 30, 60 and 60 min respectively, before the administration of pentylenetetrazole (i.p, 90 mg/kg).


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast