Words similar to carbapenems
Example sentences for: carbapenems
How can you use “carbapenems” in a sentence? Here are some example sentences to help you improve your vocabulary:
The Tyr228 mutants exhibited increased K m values for 8 of the 9 substrates tested, with the smallest changes in K m observed when the carbapenems were used as the substrate.
As a first approximation of substrate binding, we examined the steady-state kinetics of 4 cephalosporins, 2 penicillins, and 3 carbapenems (Tables 3, 4, 5) and compared the K m values of the mutants with those of wild-type L1.
Three carbapenems were also used as substrates for L1, and biapenem, imipenem, and meropenem exhibited K m values of 32 ± 1 μM, 57 ± 7 μM, and 15 ± 4 μM and k cat values of 134 ± 4 s -1, 370 ± 5 s -1, and 157 ± 9 s -1, respectively (Table 5).
On the other hand, the K m and k cat values for the I164A mutant when the penicillins or carbapenems were used as substrates were very similar to those numbers exhibited by wild-type L1 (Tables 4and 5).
When the carbapenems were used as substrates however, the changes in K m values were relatively smaller than with the other substrates, and 2- to 37-fold changes in k cat were observed (Table 5).
Loading...