Example sentences for: calpain

How can you use “calpain” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Cathepsin B is a lysosomal cysteine protease, the expression of which is increased in different tumors, including human brain, lung, colon, and breast tumors [ 19 ] . Calpastatin is a physiological protease inhibitor that acts specifically on calpain, a calcium-dependent cysteine protease.

  • Experiments using various protease inhibitors indicated that the changes in complex mobility were due to inhibitory effects of PKA on the protease calpain.

  • Calpain is an exception to the pairing rule.

  • The cleavage of calpastatin by caspases initiates the apoptotic cascade in certain neurological disorders [ 20 ] . It is possible that increased expression of calpastatin may control calpain activity thereby limiting extent of proteolysis during capillary sprouting.

  • However, additional data are clearly needed to further investigate the roles of calpain proteolysis and proteasome-mediated proteolysis on chromosome segregation as well as the numerous other potential molecular mechanisms of aneuploidy.


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