Example sentences for: calpain

How can you use “calpain” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Besides inhibiting proteasome activity, the peptide aldehyde proteasome inhibitors have been also reported to repress certain lysosomal cysteine proteases and calpains [ 49 ] . The finding that MG-132 can obstruct the casein degrading activity of the calcium-dependent protease calpain [ 50 ] appears relevant to oocyte maturation.

  • Experiments using various protease inhibitors indicated that the changes in complex mobility were due to inhibitory effects of PKA on the protease calpain.

  • The cleavage of calpastatin by caspases initiates the apoptotic cascade in certain neurological disorders [ 20 ] . It is possible that increased expression of calpastatin may control calpain activity thereby limiting extent of proteolysis during capillary sprouting.

  • 1D,1E) suggest that the MG-132-induced transient inhibition of proteasomal and calpain activities during meiosis I predisposed oocytes to abnormal chromosome segregation.

  • However, additional data are clearly needed to further investigate the roles of calpain proteolysis and proteasome-mediated proteolysis on chromosome segregation as well as the numerous other potential molecular mechanisms of aneuploidy.


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