Example sentences for: calreticulin

How can you use “calreticulin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mefloquine (80 μM) upregulated the transcription of four of five ER resident chaperones, GRP78, PDI, GRP94 and calreticulin, GADD153 and PERK (one way ANOVA P < 0.05, n = 20, FC > 1.3, Table 2).

  • The Rat Genome U34 array was found to contain probe-sets representing the ER chaperones glucose-regulated protein (GRP) 78, protein disulfide isomerase, GRP94, calreticulin and endoplasmic reticulum protein 29 (EPR29), GADD153 and PERK.

  • indicating a possible role for HSP70 in fertilization [ 41 ] ). An egg-surface sperm receptor, identified on sea urchin oocytes, bears a sperm-binding domain with sequence similarity to HSP70 and its recombinant protein binds sperm and inhibits fertilization in vitro [ 42 ] . Among the other molecular chaperones described here, calreticulin has been found in oocytes from a number of species [ 43 ] . Interestingly, Munoz-Gotera et al.

  • That mammalian calreticulin is a zinc-dependent protein [ 62] raises the possibility that zinc limitation prevents the proper activity of this protein in yeast, leading to unfolded ER proteins and triggering the subtle increase in expression of genes that participate in the UPR.

  • However, a potential connection between zinc and the UPR is the protein calreticulin, an ER protein-folding chaperone that acts on glycosylated proteins [ 61].


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