Example sentences for: calpains

How can you use “calpains” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the case of papain-like proteases - calpains, transglutaminases and NH 2 -acetyltransferases - the three-stranded sheet of the core is incorporated into β-barrel with five to eight constituent strands (Figure 2).

  • Besides inhibiting proteasome activity, the peptide aldehyde proteasome inhibitors have been also reported to repress certain lysosomal cysteine proteases and calpains [ 49 ] . The finding that MG-132 can obstruct the casein degrading activity of the calcium-dependent protease calpain [ 50 ] appears relevant to oocyte maturation.

  • Anti-RA-1 antibodies are directed towards domains 3 and 4 of calpastatin, the natural inhibitor of calpains, which are members of the cysteine proteinases that have been implicated in articular damage [ 13].

  • MG-132 can also inhibit calpains [ 50 ] which are needed for cell cycle progression [ 52 ] and cyclin degradation [ 53 ] . Previous studies [ 5 55 ] have shown that an inverse relationship usually exists between the proportions of arrested MI oocytes and MII oocytes exhibiting PCS.


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