Words similar to cacagtg
Example sentences for: cacagtg
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RSS were initially identified as a conserved heptamer (consensus CACAGTG) and a conserved nonamer (consensus ACAAAAACC) separated by a less conserved spacer of either 12 ± 1 or 23 ± 1 base-pairs (bp) [ 44].
With respect to the heptamer (canonical sequence: CACAGTG), the CAC sequence bordering the recombination site is the most conserved segment of the sequence [ 32 ] , and mutation of these nucleotides has been found to decrease V(D)J joining in transfection assays using recombination substrates [ 40 ] . Because the sequence of the canonical RSS heptamer is palindrome, we speculate that the TGTG sequence may be sufficient for KRC/ZAS-C binding.