Example sentences for: breakpoints

How can you use “breakpoints” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Recent studies have characterized several evolutionary breakpoints in common chimpanzee and other great ape species including pericentric inversions and a chromosome translocation [ 7 8 9 ] . We present here a refinement of the breakpoint associated with a previously identified pericentric inversion of the human 15q11-q13 orthologous region in common chimpanzee (XVp) to a region containing multiple segmental duplications [ 1 2 10 ] .

  • None of these sequences are known to predispose to genomic rearrangements, although short stretches of identical sequence are often found at the sites of germline translocation and deletion breakpoints [ 20 21 22 ] . Genomic analysis of the parents and siblings of Case 2 indicated that the mutation was sporadic.

  • We investigated the L1 sequence composition at the breakpoint in 5' truncated L1s by collecting 15 nucleotides of L1 sequence upstream and downstream of the position at which the L1 had been truncated; we were unable to detect any consensus nucleotides at these breakpoints (data not shown).

  • For example, for the BXD set, if one assumes a random and independent distribution of breakpoints across strains and a random distribution of markers, it would take a map with about 2,700 markers to define 95% of the 1,536 SDPs.

  • There is mounting evidence for the role of transposable elements in the origin of inversion breakpoints in D. melanogaster and other species [ 63, 64, 65].


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