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Example sentences for: breakpoints

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Interstitial triplications have also been described, and these tend to utilize variable distal breakpoints common to idic(15) chromosomes [ 13 ] . Triplications are associated with a phenotype analogous to that for idic(15) when maternally-derived [ 7 12 13 ] .
To test whether the inversion breakpoints occur at a conserved distance from the 5' or 3' ends of the L1 elements, the start and the end positions of the 5' inverted L1 segment were compared using a scatterplot diagram for each inverted L1 with TSDs (Figure 6a).
The "spline function" (bottom row, left) and "uniform" (bottom row, right) deconvolution methods use the default input parameters (smoothing and breakpoints) determined using the gamma distribution fit to this data (top row, left) (see Methods).
Direct sequencing of the deletion junction amplicons revealed the location of the intronic breakpoints.
Knowing the precise location of breakpoints in RI lines also makes it possible to map modifier loci of mutations by making and phenotyping a set of different F1 crosses made between inbred carrier stock (for example, a knockout carried on a C57BL/6 background) and fully typed RI lines.