Words similar to bmps

Example sentences for: bmps

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Studies were then carried out to further characterize Smad1 interaction with HsN3 and Az in mammalian cells and test a functional role of these interactions in the signaling pathways of BMPs as detailed below.
Thus, BMPs 6, 7, and 60A stimulate dendritic growth in cultured sympathetic neurons derived from either perinatal or adult ganglia in the absence of effects on cell survival or axonal growth [ 15 16 17 ] . BMP-7 has also been shown to enhance dendritic growth in hippocampal, cortical and spinal motor neurons [ 18 19 20 ] .
Most notably, the neural-plate explant assay has defined the concentration-dependent role that ventrally expressed Shh plays in opposing dorsally expressed bone morphogenetic proteins (BMPs) to pattern the neural tube [ 2 ] . The assay demonstrates that the Hh-signaling cascade can distinguish between small concentration differences in the Hh ligand to instruct the differentiation of specific neuronal cell types.
Smad1, as one of the three known R-Smads of BMPs, has been extensively studied within the scope of its phosphorylation, interaction with Smad4, nuclear translocation, DNA binding and protein-protein interactions related to its function as a transcriptional regulator.
We have so far identified two functional outcomes of the observed physical interaction between Smad1, HsN3 and Az in the signaling pathways of BMPs.