Example sentences for: bmps

How can you use “bmps” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Because SC were occasionally found juxtaposed to developing follicles, blood vessels and secondary interstitial cells, one cannot exclude the possibility that the SC-derived BMPs may have paracrine functions.

  • For example, follistatin binds both activin and BMP-7 avidly but competes weakly or not at all with the type I receptor for BMP-4 binding [ 25 45 ] , whereas noggin binds to BMPs -2 and -4 with greater affinity than BMP-7 [ 46 ] . Whether BMP-5 function can be antagonized by noggin or follistatin has not been previously reported, but our results suggest that simultaneous addition of either antagonist with BMP-5 significantly inhibits the dendrite-promoting activity of BMP-5 in a concentration-dependent manner.

  • The expression of the family of BMPs (ligands, receptors and a binding protein) in the fundamental cell types of the dominant follicles (DF) argues for a physiological role of an intrinsic BMP in directing growth and cell fates in the DF.

  • Bone morphogenetic proteins (BMPs) are secreted signaling molecules of the TGF-β superfamily that have been implicated in the control of a host of critical developmental phenomena in the central and peripheral nervous systems [ 1 2 3 ] . BMP-5, one of the more prominently expressed BMPs in the nervous system, has been detected in multiple regions of the nervous system throughout development and into adulthood [ 3 4 5 6 ] , yet its biological activities in the nervous system are not well defined.

  • BMPs have been divided into subgroups based on structural and evolutionary considerations [ 8 ] . Although closely related BMPs have been shown to elicit distinct cellular responses [ 5 9 10 11 12 13 ] , members within a subgroup often display conservation of not only structure, but also function [ 4 5 6 14 ] . BMP-5 belongs to the 60A subgroup of BMPs, which also includes BMP-6/Vgr-1, BMP-7/OP-1, BMP-8a/OP-2, BMP-8b and Drosophila 60A [ 3 8 ] . Other members of the 60A subgroup have been shown to modulate neuronal morphogenesis through selective effects on dendrites.


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