Words similar to bmps

Example sentences for: bmps

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The BMPs are prominently expressed during embryonic tissue induction (reviewed by [ 18]).
For example, follistatin binds both activin and BMP-7 avidly but competes weakly or not at all with the type I receptor for BMP-4 binding [ 25 45 ] , whereas noggin binds to BMPs -2 and -4 with greater affinity than BMP-7 [ 46 ] . Whether BMP-5 function can be antagonized by noggin or follistatin has not been previously reported, but our results suggest that simultaneous addition of either antagonist with BMP-5 significantly inhibits the dendrite-promoting activity of BMP-5 in a concentration-dependent manner.
The role of the BMPs has been studied in fracture healing in rats [ 2, 3, 5], mice [ 4, 7, 8], and rabbits [ 6] and in healing of spinal fusions in rabbits [ 9].
It is becoming increasingly evident that BMP signaling is regulated not only by the spatiotemporal expression of BMP ligands and receptors, but also by relative levels of soluble BMP antagonists, which directly bind BMPs and prevent functional receptor/ligand interaction [ 1 24 25 26 27 28 ] . The different BMP antagonists bind to BMPs and other TGF-β family members with varying degrees of specificity.
Earlier studies have demonstrated the expression of BMP-4 transcripts in developing avian sympathetic ganglia [ 49 ] , suggesting the presence of multiple BMPs in sympathetic ganglia throughout development.