Example sentences for: blocker

How can you use “blocker” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Optical imaging of neural activity evoked by electrical stimulation in the cultured rat suprachiasmatic nucleus (SCN) revealed that the spread of depolarization was inhibited by gap junction blockers (halothane, octanol) but not by a blocker of voltage-depended Na +channels.

  • , carteolol, had normal calcium cycling, normal myocardial energetics,normal β 1 receptor density as well as regression of myocytehypertrophy and reduced connective tissue content [ 18 ] . Furthermore, administration of carteolol hasbeen reported to prevent the development of virally induced cardiomyopathyin a murine model [ 25 ] . In a canine modelwith left ventricular dysfunction produced by multiple sequentialintracoronary microembolizations, long term treatment with metoprolol,a β 1 -selective blocker, has been reported to preventthe progression of LV systolic dysfunction and LV chamber dilatation [ 26 ] . Similarly, our present findings onthe effect of carvedilol indicated improvement of left ventricularfunction and smaller LV volumes.

  • A double-blind, active-controlled hypertension component is designed to compare the rate of fatal coronary heart disease (CHD) or nonfatal myocardial infarction (MI) (the primary endpoint) in high-risk hypertensive participants, aged 55 years or older, between those randomized to treatment initiated with a diuretic (chlorthalidone) and treatment initiated with each of three alternative antihypertensive drugs: a calcium-channel blocker (amlodipine), an angiotensin-converting enzyme (ACE)-inhibitor (lisinopril), or an alpha-adrenergic blocker (doxazosin).

  • Many studies have shown that chronic intravenous infusion of norepinephrine is sufficient to cause hypertrophy, and that various forms of hypertrophy are linked to a decrease in either beta-adrenergic receptor density or a decreased responsiveness to beta-adrenergic stimulation [ 46 48 49 56 57 58 59 60 61 62 63 ] . Barth, for example, showed that norepinephrine infusion induced left ventricular hypertrophy that could be prevented by an adrenergic-receptor blocker [ 58 ] . It has been suggested that ornithine decarboxylase is a link between beta-adrenoreceptors and stimulation of tissue growth factor, which results in hypertrophy [ 64 ] . However, recent studies have focused on alpha-adrenergic reception as a mediator of cardiac hypertrophy [ 35 ] , although some question the role of the alpha-adrenergic receptor as a hypertrophic mediator in vivo [ 34 ] . To date, no published studies of which we are aware have examined alpha-adrenergic reception and the development of cardiac hypertrophy with iron deficiency.

  • The sections were treated for 5 min with 3% H 2 O 2 , followed by a 10 min incubation with the universal blocker, Cas-block (Zymed).


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