Example sentences for: blocker

How can you use “blocker” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Results presented here show that TEA serves as an effective, though partial, blocker of the osmotic water permeability mediated by human AQP1 channels expressed in a heterologous mammalian cell line and by native AQP1 channels in isolated rat renal descending thin limbs of Henle's loops.

  • A double-blind, active-controlled hypertension component is designed to compare the rate of fatal coronary heart disease (CHD) or nonfatal myocardial infarction (MI) (the primary endpoint) in high-risk hypertensive participants, aged 55 years or older, between those randomized to treatment initiated with a diuretic (chlorthalidone) and treatment initiated with each of three alternative antihypertensive drugs: a calcium-channel blocker (amlodipine), an angiotensin-converting enzyme (ACE)-inhibitor (lisinopril), or an alpha-adrenergic blocker (doxazosin).

  • Following the injection of the blocker, the researchers observed an increase of the brain chemical CRF in the amygdala, a portion of the brain involved with the emotions of fear and aggression.

  • Many studies have shown that chronic intravenous infusion of norepinephrine is sufficient to cause hypertrophy, and that various forms of hypertrophy are linked to a decrease in either beta-adrenergic receptor density or a decreased responsiveness to beta-adrenergic stimulation [ 46 48 49 56 57 58 59 60 61 62 63 ] . Barth, for example, showed that norepinephrine infusion induced left ventricular hypertrophy that could be prevented by an adrenergic-receptor blocker [ 58 ] . It has been suggested that ornithine decarboxylase is a link between beta-adrenoreceptors and stimulation of tissue growth factor, which results in hypertrophy [ 64 ] . However, recent studies have focused on alpha-adrenergic reception as a mediator of cardiac hypertrophy [ 35 ] , although some question the role of the alpha-adrenergic receptor as a hypertrophic mediator in vivo [ 34 ] . To date, no published studies of which we are aware have examined alpha-adrenergic reception and the development of cardiac hypertrophy with iron deficiency.

  • Experimental rats were administered an estrogen receptor blocker, and later at postnatal day 70 these rats responded to estrogen administration with an increase in CC size; an effect opposite of what would be expected.


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