Words similar to blockade
Example sentences for: blockade
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Earlier studies have shown that blockade of caspase-8 activation in HeLa cells and deletion of caspase-8 in Jurkat cells prevented activation of downstream signaling, resulting in a failure of the cells to undergo apoptosis in response to TRAIL [ 46 ] . Similarly, another group has demonstrated that apoptosis induced by S. aureus in bovine mammary epithelial (MAC-T) cells utilizes a mechanism involving caspases-8 and -3, which are two key components of the proteolytic cascade that leads to apoptosis [ 30 ] . Results from the current study demonstrate a two-fold increase in caspase-8 activation upon infection with S. aureus (Fig.
US president John F. Kennedy imposed a naval blockade on the island to ensure no more missiles arrived and insisted that the existing ones be removed.
Hormonal signal transduction and steroidogenesis can be affected by changes in intracellular and extracellular concentrations of inorganic ions, cellular resting membrane potential, and cell size [ 29 30 35 54 55 56 57 58 59 ] . Blockade of 4-AP sensitive K +channels in non-nerve, non-muscle cells can lead to changes in transmembrane ion gradients, membrane potential and cell volume [ 42 60 ] . On this basis, we determined the effects of 24 h exposure to 4-AP on GC size, membrane potential and intracellular potassium ([K +] in ).
2 ml into the bladder the distal, cut end of the pelvic nerve was stimulated with a long train (5 Hz; 1 msec pulse width; 60 sec train; 30-300 (uamps) to elicit a prolonged contraction displaying two phases: Phase I, a rapid contraction and Phase II, a plateau phase [ 20 21 ] . Phase I is resistant to atropine, and therefore is mostly due to non-adrenergic, non-cholinergic activation, whereas Phase II is highly sensitive to muscarinic blockade [ 21 ] . Olanzapine (n = 4) and risperidone (n = 4) were administered (0.
Of particular interestis the use of carvedilol [ 12 13 14 15 16 ] .Carvedilol is a novel multiple-action neurohormonal antagonist.Its primary activities are nonselective β-adrenoceptor blockade,vasodilatation (mediated through α1-adrenoceptor blockade), andantioxidant activity [ 12 ] . In many clinical studies,carvedilol has been shown to improve left ventricular function andsymptoms in patients with ischemic heart disease or idiopathic dilatedcardiomyopathy [ 13 14 15 16 ] andto dramatically reduce mortality [ 17 ] .However, it remains unclear how carvedilol improves ventricular functionin heart failure.
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