Words similar to biomarker
Example sentences for: biomarker
How can you use “biomarker” in a sentence? Here are some example sentences to help you improve your vocabulary:
One reason for using FPR and TPR from mammography as a standard is that, unlike biomarker measurements in nested case-control studies, in mammography studies there is a biopsy at the time of a positive test.
Lysophophatidic Acid (LPA) is a member of this class of compounds, and its plasma levels have been proposed as a potential biomarker for ovarian cancer [ 16 17 ] . LPA is a family of related molecules with molecular weights in the vicinity of 400 to 600 Daltons, and a variety of LPA species has been reported to be increased in malignant ascites from patients with ovarian cancer as detected by electrospray ionization mass spectrometry (ESI-MS) [ 18 ] . LPA related species have also been reported to be increased in plasma samples from patients with ovarian cancer using a combination of thin layer chromatography (to isolate an "LPA band" from patient plasma) followed by ESI-MS.
Individual genes observed to be significantly different by Affymetrix analysis and in both sets of SYBR Green RT-PCR experiments were screened as potential biomarker candidates.
All clinical samples for biomarker analysis were harvested and handled in accordance with full Institutional Review Board-approved protocol, and study participants had signed the study informed consent prior to any study-related procedures.
Nevertheless, the results described here demonstrate that human blood samples can serve as surrogate specimens for biomarker investigations in cancer patients and imply that large-scale gene expression analysis may be a useful approach for characterization of drug activity from clinical trial samples.
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