Example sentences for: bdnf
How can you use “bdnf” in a sentence? Here are some example sentences to help you improve your vocabulary:
The pufferfish BDNF gene is located in the scaffold_551.
A strong BDNF signal was found over the hair cells of control animals and an occasional immature hair cell also showed a BDNF signal in the Brn3c null mutants.
Past work has shown that BDNF and NT-3 appear to shift in their expression into inner hair cells around birth or are lost in the ear and other parts of the nervous system [ 6 10 20 23 ] . It has been suggested that other neurotrophins may come into play in the ear [ 11 ] . However, the apex of Brn3c null mutants, which retains most of the spiral neuron afferents at 6-month, shows no formation of mature hair cells at any time surveyed here (P0, P8, P10).
Four ears each of Brn3c null mutants (P0 and P8) and control littermates were embedded in paraffin, sectioned and probed for the presence of BDNF and NT-3 mRNA using the in situ technique previously described [ 7 ] . Sections were lightly counterstained and viewed with bright and dark field microscopy.
[ 5 ] . BDNF transiently stabilizes silent NM synapses during the period of transition from polyneuronal to mononeuronal innervation of skeletal muscle fibers [ 6 ] . BDNF and CNTF cooperatively affect efficiency of embryonic xenopus neuromuscular synapses in culture [ 7 8 ] . BDNF stimulates transmitter release from neuromuscular synapses [ 9 ] and enhances the efficiency of transmission at the neuromuscular synapse [ 10 ] . BDNF, together with NT-3, can restore neuregulin levels and a normal distribution of AchR at the neuromuscular junction blocked with curare [ 11 ] . BDNF, in conjunction with fibronectin, increases spontaneous synaptic currents in the cultured embryonic xenopus neuromuscular junction [ 12 ] . BDNF down-regulates AchR clustering, most likely by binding to TrkB expressed in myocytes [ 13 ] . BDNF downregulates agrin levels in muscle but increases neuregulin in ventral horn spinal motor neurons at the time when they form neuromuscular synapses [ 14 ] .
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