Example sentences for: bdm

How can you use “bdm” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • BDM inhibits actin incorporation in mammalian cells

  • [ 11 17 18 ] . A role for nm-myosinII may exist, given its localization and that other perturbations that affect myosin function - myosin S1 microinjection, ML-7 treatment, and expression of dominant negative nm-myosinII constructs and have similar effects to BDM treatment [ 5 7 12 ] . However, a study in chick dorsal root ganglia neurons where nm-myosinII was inactivated using chromophore assisted laser inactivation saw no effect on retrograde flow rates [ 19 ] . We know now that BDM does not in fact inhibit nm-myosinII.

  • As mentioned, Listeria infected cells were used to confirm that BDM does not directly affect actin dynamics.

  • Interestingly, Listeria bacteria continue to move in the presence of BDM, while the leading edge of the infected cell stops ruffling.

  • Understanding how these effects are mediated can help us learn from BDM and reinterpret experiments that made use of it, while working to find new and better inhibitors.


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