Words similar to bdm

Example sentences for: bdm

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To ask whether the loss of leading edge localization was specific to the Arp complex, we examined the localization of VASP and WAVE1 with BDM treatment.
Both VASP and WAVE function in controlling actin dynamics at the leading edge - VASP is thought to promote filament elongation, and WAVE, actin nucleation [ 25 26 ] . Both VASP and WAVE1 were de-localized from the leading edge after 1 min of BDM treatment [Figure 4].
BDM treatment thus seems to disrupt actin dynamics specific to the plasma membrane and this may provide a clue to both the mechanism of BDM inhibition and the relationship of actin dynamics at the plasma membrane.
Understanding how these effects are mediated can help us learn from BDM and reinterpret experiments that made use of it, while working to find new and better inhibitors.
Similar to Arp3, the localization of these proteins was not disrupted by cytochalasin D treatment, or by the combination of cytochalasin D and BDM [Figure 4].