Words similar to attenuated
Example sentences for: attenuated
How can you use “attenuated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Preincubation with a TGFβ-RII blocking antibody attenuated the TGFβ 1 induced pattern, contrary to SMAD 4 deleted BxPC-3 cells.
Fabry disease is an X-linked disorder resulting in reduced activity of the lysosomal enzyme α-galactosidase A [ 1 2 ] . This results in the systemic accumulation of D-galatosyl conjugates, particularly globotriosylceramide (Gb3) [ 3 4 ] . Although the disorder is heterogeneous, patients suffer renal, cardiovascular and cerebrovascular complications [ 4 ] . Enzyme replacement therapy has recently shown to have an effect on resting cerebral blood flow abnormalities and on other organ systems functions [ 5 6 ] . In the cerebrovascular system there is an increased incidence of stroke together with vessel ectasia [ 7 ] . This may be related to the progressive accumulation of storage material in the cerebral vessel or possibly, may be due to an abnormality of vessel function [ 8 9 ] . The cerebrovascular complications are distributed predominantly in the posterior circulation with a progressive increase over time in the posterior distribution of small vessel disease as found on T 2 -weighted images or fluid attenuated inversion recovery (FLAIR) MR [ 7 10 11 ] . It likely that such high signal lesions on MR images represent ischemic small vessel disease, however, there are no neuropathological-radiological correlative studies confirming this assumption.
Expression of an attenuated diphtheria toxin gene under the control of rhodopsin promoter results in the specific elimination of rod photoreceptors in the retina [ 34].
Linking of the TGFβ-R pathway to the Ras/MAPK pathway is dependent on a functional SMAD4 gene product, because TGFβ 1 induced gene expression and activation of Ras and ERK1/2 is attenuated by the TGFβ-RII blocking antibody only in SMAD4 wild type cells, whereas in the SMAD4 deleted BxPC-3 cells, no such influence was observable.
PPAR agonists reduced the 25-OH-cholesterol induced c-jun activation and attenuated the cytotoxicity.
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