Example sentences for: attenuate

How can you use “attenuate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Also, neurons were cultured with cAMP analogs or preincubated with nerve growth factor (NGF), treatments known to attenuate the overall inhibitory effects of myelin [ 35, 36].

  • MAdCAM-1 is normally expressed in the gut, and its expression is dramatically amplified during inflammation [ 2 3 ] . The functional significance of increased appearance of MAdCAM-1 in IBD is supported by several reports which show that immunoneutralization of either MAdCAM-1 or its ligand, the α4β7 integrin, attenuate inflammation and mucosal damage in animal models of colitis [ 8 9 10 ] . However, since monoclonal antibodies directed against other ECAMs, particularly VCAM-1, can as well reduce disease activity in colitis models [ 11 12 13 14 ] , the literature suggests that MAdCAM-1 is probably necessary, but insufficient for the maximal penetrance of experimental and probably also clinical IBD.

  • Estrogen has been shown to enhance baroreflex sensitivity [ 21] and attenuate the response of heart rate to administration of isoproterenol in rats [ 22].

  • Here we examined if this differential response is limited to cells that normally metabolize bile acids, and whether high level expression of an intracellular bile acid binding protein can attenuate the cytotoxic response of McNtcp.

  • Since TNFRSF induces cell death by causing an efflux of glutathione (GSH) in other cell types [ 42 ] we sought to determine if pretreatment of CLENDO cells with GSH would attenuate lethality associated with TNFα treatment.


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