Words similar to atf-bpti

Example sentences for: atf-bpti

How can you use “atf-bpti” in a sentence? Here are some example sentences to help you improve your vocabulary:

Systemic and local delivery of an adenovirus encoding ATF have been shown to inhibit the growth of primary tumour implants as well as of tumour metastasis in different animal models [ 18 19 ] . In the ATF-BPTI chimeric protein, ATF has two functions (1) the anti uPA effect with its known angiostatic activity and (2) delivery of BPTI at the tumour site due to over-expression of uPAR on tumour and endothelial cells.
The Ad Adapt mhAB encodes for a murinised form of the human ATF-BPTI [ 21 ] . In this construct the mhAB, is preceded by the native secretion signal peptide of the human urokinase.
Therefore a bronchial squamous cell carcinoma and an adenocarcinoma with different microvascular density (MVD) were selected to assess the inhibition effect of the ATF-BPTI.
In this extent, ATF-BPTI is similar to the MMPs inhibitors, in that their best indication would probably be for treatment of residual disease or small metastases.
The murinised version of ATF-BPTI differs by four amino acids from the human version It was shown to bind to the rat receptor and to inhibit plasmin activity in a rat model [ 21 ] . BPTI (commercialised as aprotinin) is a serine protease inhibitor prepared from bovine lung tissue which dose dependently inhibits human trypsin, plasmin and kallikrein.