Words similar to atf-
Example sentences for: atf-
How can you use “atf-” in a sentence? Here are some example sentences to help you improve your vocabulary:
Examining the region of ATF-2 that showed HAT activity, the authors found some sequence similarity and at least one motif resembling the acetyltransferase superfamily and concluded that ATF-2 contained a GCN5-like acetyltransferase domain [ 40].
The JNK pathway is involved in apoptosis [ 13 ] , arginine vasopressin-induced increases in smooth muscle α-actin in vascular smooth muscle cells [ 14 ] as well as in phosphorylation of transcription factors c-jun, ATF-2 and ELK-1 and phosphorylation of Na-K-2CI cotransporter [ 15 ] . The p38 pathway has been implicated in apoptosis [ 16 ] , neointimal hyperplasia after vascular injury [ 17 ] as well as angiotensin ll-induced contraction in vascular smooth muscle [ 18 ] .
Thus, the relationship between ATF-2 and the GCN5-like acetyltransferase superfamily seems to be invalid, leaving the structural basis for the reported acetyltransferase activity of ATF-2 an open issue.
Furthermore, complexity analysis using the SEG program, with the parameters adjusted for decomposition of a protein into globular and non-globular regions [ 41], predicted that the entire region of the ATF-2 protein between the amino-terminal zinc finger and the carboxy-terminal helical b-ZIP was unstructured.
The region designated as having HAT activity and containing the acetyltransferase domain shows poor conservation between orthologs and closely related paralogs of the ATF-2 family, especially in the sequence identified as the most prominent A motif of the acetyltransferase family (Figure 7).
Loading...