Example sentences for: asp

How can you use “asp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A naturally occuring Asn57Asp polymorphism may be associated with JOAG [ 39 ] which, if truly disease-associated, would suggest the functional importance of N-linked glycosylation.

  • Protein protonation states were modeled as in the related HIV-1 protease MD simulation study [ 56 ] . All protein residues were modeled in their charged state except for one of the two aspartic acid groups (Asp 25 and Asp 25') in the active site since previous studies [ 57 58 59 ] have shown that at least one of these two aspartic acids is protonated.

  • Mutation of Asp355 by asparagine (the non charged analog of aspartic acid), or by histidine or lysine (that have a positively charged side chain) or by alanine (neutral), inactivated PAI-1.

  • For those readers seeking an update on this challenging area, we would direct your attention to the Alzheimer Research Forum Web page (http://www.alzforum.org/new/detailprint.asp?id=1135), where you will find an excellent review of the literature as well as a series of evaluations of how our data fit into existing scenarios and models regarding cholesterol, statins, cerebral amyloidosis, and the cognitive failure of Alzheimer disease.

  • Single site mutations within the segment Asp355-Arg356-Pro357 of PAI-1 yield Gdn-HCl activatable inhibitors that can still form SDS stable complexes with plasminogen activators, with second order inhibition constants that are similar to the native inhibitor.


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