Words similar to asn
Example sentences for: asn
How can you use “asn” in a sentence? Here are some example sentences to help you improve your vocabulary:
The fully edited rat 5-HT 2C receptor exhibits reduced agonist efficacy or ability to interact with G proteins compared to the unedited receptor (Ile157-Asn159-Ile161) in transfected cells [ 39 ] . Interestingly, 5-HT elicits a larger response (see Fig.
Substitution of human myocilin Asn 57 with Ser was accomplished using the QuickChange XL Site-Directed Mutagenesis kit (Stratagene) according to the manufacturer's instructions.
The middle histidine of the histidine triad (His96 in human Fhit), which is critical for hydrolysis of ApppA by Fhit [ 14 16 ] , is not necessary for tumor suppression [ 17 18 ] . Nonetheless, wild-type and His96Asn forms of Fhit are saturated by ApppA in the low micromolar range and form stable complexes with non-hydrolyzable ApppA in which two ApppA analogs are bound per Fhit dimer and all phosphates cluster on one surface of the protein [ 16 ] . These observations suggested that Fhit-substrate complexes may be the active, signaling form of Fhit and that the function of the catalytically essential histidine may be to terminate the lifetime of signaling complexes [ 16 ] .
For 10 of the 18 amino acids with more than one codon (Arg, Asn, His, Ile, Leu, Lys, Phe, Pro, Thr, Tyr), the most frequently used codon in D. willistoni differs from that in D. melanogaster . All 10 of these changes in synonymous codon usage involve D. willistoni most frequently using an A- or T-ending (or beginning, for example, Leu) codon with D. melanogaster using a G- or C-ending (or beginning) codon, supporting a trend identified originally using only the Adh coding sequence [ 41].
His114 corresponds to His98 of Fhit, which was localized in low barrier hydrogen-bonding distance to the α-β bridging oxygen of a bound ApppA analog in co-crystal structure with Fhit His96Asn [ 35].
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