Words similar to asn
Example sentences for: asn
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Two-thirds of all sequenced metallo-β-lactamases have an Asn at position 233 [ 41 ] , and this residue was predicted [ 42 ] and shown [ 43 ] to be involved with substrate binding and activation by interacting electrostatically with the substrate β-lactam carbonyl.
His114 corresponds to His98 of Fhit, which was localized in low barrier hydrogen-bonding distance to the α-β bridging oxygen of a bound ApppA analog in co-crystal structure with Fhit His96Asn [ 35].
[ 35 ] suggested that Glu65 ( a 4) and Asn183 ( a 2) are occupied by Chl a . Loss of the latter Chl apparently resulted in loss of 'out-lying' Chl b in site b2, which is near a 2 in the 3-dimensional structure.
In all the available organisms, the four central protomers of the midasin polypeptide, AAA2, AAA3, AAA4 and AAA5, possess canonical Walker A and B motifs, as well as the critical Asn in sensor 1 and Arg in sensor 2 that are required for proper function in other AAA proteins [ 15 ] . The presence of these critical residues, taken together with their higher level of average sequence conservation (Table 1), suggests that the four central protomers all retain an active enzymatic function.
This suggests that the 55/57-kDa human myocilin doublet is due to differential glycosylation and that the site of N-linked glycosylation on human myocilin is Asn 57.