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Example sentences for: asf

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Involvement of ASF/SF2 in the regulation of
ASW was cloned a third time as a message that is increased in cells lacking the splicing factor ASF/SF2 [ 37].
Surprisingly, ASF/SF2 did not affect splicing of the ASW message but rather destabilized the mRNA [ 37].
TOP1 has been shown to interact with many proteins including components of the holo TFIIIC complex [ 1 ] , TFIID [ 2 ] , p53 [ 3 ] , SV-40 large T antigen [ 4 ] , nucleolin [ 5 ] , the RING finger protein topors [ 6 ] , the RNA splicing factors PSF/p54 nrb [ 7 ] and SF2/ASF [ 8 ] , the cell cycle regulatory protein ARF [ 9 ] , RNA pol II complex [ 10 11 ] , and HTLV type 1 tax oncoprotein [ 12 ] . TOP1 also interacts with a variety of unidentified proteins involved in its phosphorylation, ubiquitination and sumoylation [ 13 14 15 16 17 ] .
ASW mRNA is interesting because sex-specific splicing of doublesex mRNA in Drosophila , a sex-determining gene for which the mammalian DMRT genes were named, is mediated in part by ASF/SF2 [ 38].