Words similar to asd
Example sentences for: asd
How can you use “asd” in a sentence? Here are some example sentences to help you improve your vocabulary:
C57BL/6J; BMP; bone morphogenetic protein; ASD, anterior segment dysgenesis; ERG, electroretinography.
In humans with ASD, the phenotype is variable even between patients with mutations in the same gene, and the severity of clinically observable dysgenesis does not correlate with IOP.
In this study, we analyzed mice heterozygous for a null allele of Bmp4 ( Bmp4 tmlBlh ) [ 24 ] to determine if decreased functional gene dosage contributes to ASD and elevated IOP.
For FOXC1 and PAX6, both haploinsufficiency and increased gene dosage due to gene duplication result in abnormal ocular development [ 10 11 12 13 ] . Similarly, a mutation in PITX2 that results in increased transcriptional transactivation causes ASD [ 14 ] .
This work functionally demonstrates that BMP4 is a good candidate to cause human ASD and developmental glaucoma.