Words similar to asd
Example sentences for: asd
How can you use “asd” in a sentence? Here are some example sentences to help you improve your vocabulary:
In this study, we analyzed mice heterozygous for a null allele of Bmp4 ( Bmp4 tmlBlh ) [ 24 ] to determine if decreased functional gene dosage contributes to ASD and elevated IOP.
The abnormalities affect a variety of anterior segment tissues including the drainage structures of the iridocorneal angle and are similar to those reported in human patients with ASD and glaucoma [ 36 37 38 ] . The absence of detectable Bmp4 expression in the drainage structures suggests that BMP4 produced by the ciliary body and/or iris may act as a growth and differentiation factor during angle development.
For FOXC1 and PAX6, both haploinsufficiency and increased gene dosage due to gene duplication result in abnormal ocular development [ 10 11 12 13 ] . Similarly, a mutation in PITX2 that results in increased transcriptional transactivation causes ASD [ 14 ] .
Heterozygous Bmp4 mutant mice have a variety of ocular abnormalities including ASD, buphthalmia (enlarged eyes), and elevated IOP.
In humans with ASD, the phenotype is variable even between patients with mutations in the same gene, and the severity of clinically observable dysgenesis does not correlate with IOP.