Words similar to aptazymes
Example sentences for: aptazymes
How can you use “aptazymes” in a sentence? Here are some example sentences to help you improve your vocabulary:
For all of the aptazymes except Th3P6, the ligand-induced splicing activity was greater in a standard assay at the more stringent (3 mM) magnesium concentration (Table 1).
Construction of the tdintron aptazymes
Based on these results, the primary mechanism of activation is likely the same as has been observed for other aptazymes: ligand-induced conformational changes that stabilize functional ribozyme sequences and structures.
These results argue that both GTP and theophylline may need to be present to influence the folding pathway of the engineered Group I aptazymes.
In order to examine effector-specificity in vivo , a new series of Group I aptazymes was constructed in which the anti-theophylline aptamer was mutated to bind 3-methylxanthine (3MeX2P6) [ 34 ] . These variants proved to be responsive to 3-methylxanthine both in vitro and in vivo (Figure 6a).
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