Words similar to aptazymes
Example sentences for: aptazymes
How can you use “aptazymes” in a sentence? Here are some example sentences to help you improve your vocabulary:
Adjoining aptamers to the Group I self-splicing intron would potentially allow the control of splicing not only in vitro , but in vivo . To this end, we have attempted to generate and assay Group I aptazymes.
Thus, the responsivity of the aptazymes in vivo appears to mirror their effector specificity in vitro .
This would seem especially true in the current set of experiments, since the modulation of Thymidylate Synthase expression is known to greatly affect thymidine levels and cell growth [ 32 ] . For example, E. coli that are starved for thymine quickly die, a phenomenon known as 'thymineless death' [ 33 ] . In this respect, Group I aptazymes that may have yielded lower amounts of functional Thymidylate Synthase (e.g.
These results argue that both GTP and theophylline may need to be present to influence the folding pathway of the engineered Group I aptazymes.
The self-splicing activities of the Group I aptazymes were examined in vitro using a standard splicing assay (Table 1).