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Example sentences for: aptazymes

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Construction of the tdintron aptazymes
Based on these results, the primary mechanism of activation is likely the same as has been observed for other aptazymes: ligand-induced conformational changes that stabilize functional ribozyme sequences and structures.
These results argue that both GTP and theophylline may need to be present to influence the folding pathway of the engineered Group I aptazymes.
In contrast, aptazymes that may have yielded even modestly greater amounts of functional Thymidylate Synthase (e.g.
The time courses reveal that the extents of splicing of the aptazymes were significantly affected by the addition of theophylline (Figures 2b,2c).