Words similar to aptazymes
Example sentences for: aptazymes
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The self-splicing activities of the Group I aptazymes were examined in vitro using a standard splicing assay (Table 1).
Group I aptazymes that were dependent upon theophylline both in vitro and in vivo were engineered by conjoining the thymidylate synthase ( td ) intron with an anti-theophylline aptamer.
These results argue that both GTP and theophylline may need to be present to influence the folding pathway of the engineered Group I aptazymes.
Construction of the tdintron aptazymes
The time courses reveal that the extents of splicing of the aptazymes were significantly affected by the addition of theophylline (Figures 2b,2c).