Example sentences for: aptazymes

How can you use “aptazymes” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Adjoining aptamers to the Group I self-splicing intron would potentially allow the control of splicing not only in vitro , but in vivo . To this end, we have attempted to generate and assay Group I aptazymes.

  • Thus, the responsivity of the aptazymes in vivo appears to mirror their effector specificity in vitro .

  • This would seem especially true in the current set of experiments, since the modulation of Thymidylate Synthase expression is known to greatly affect thymidine levels and cell growth [ 32 ] . For example, E. coli that are starved for thymine quickly die, a phenomenon known as 'thymineless death' [ 33 ] . In this respect, Group I aptazymes that may have yielded lower amounts of functional Thymidylate Synthase (e.g.

  • These results argue that both GTP and theophylline may need to be present to influence the folding pathway of the engineered Group I aptazymes.

  • The self-splicing activities of the Group I aptazymes were examined in vitro using a standard splicing assay (Table 1).


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