Example sentences for: aptazyme

How can you use “aptazyme” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The negative control and aptazyme constructs were made as described except that Gp1Wt3.

  • The parental P6 aptazyme construct was generated by two overlapping oligos, Gp1Wt2 Gp1Wt2.

  • In order to convert the Group I self-splicing intron to a regulatable aptazyme, it was necessary to first identify sequences or structures in the ribozyme whose conformation might modulate splicing activity.

  • Interestingly, no growth was observed for bacteria harboring the intron Th1P6, despite the fact that this aptazyme showed the greatest activation by theophylline in vitro . The plating results were consistent and reproducible over a variety of experiments.

  • Interestingly, those aptazyme constructs that showed ligand-dependent activity closely resembled the original deletion variants that showed magnesium-dependent recovery of splicing activity.


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