Example sentences for: apoptosis

How can you use “apoptosis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 6c, 6c') may be due to a gradual turnover of α-SMA in the cells undergoing apoptosis.

  • The microvasculature of the CL is thought to be the first structure to undergo degeneration via apoptosis during luteolysis [ 2 8 ] . In contrast to information available on steroidogenic cells of the CL, a gap exists in our understanding of the factors and their associated signaling pathways that initiate apoptosis in the vascular component of the CL.

  • Earlier studies have shown that blockade of caspase-8 activation in HeLa cells and deletion of caspase-8 in Jurkat cells prevented activation of downstream signaling, resulting in a failure of the cells to undergo apoptosis in response to TRAIL [ 46 ] . Similarly, another group has demonstrated that apoptosis induced by S. aureus in bovine mammary epithelial (MAC-T) cells utilizes a mechanism involving caspases-8 and -3, which are two key components of the proteolytic cascade that leads to apoptosis [ 30 ] . Results from the current study demonstrate a two-fold increase in caspase-8 activation upon infection with S. aureus (Fig.

  • In response to DNA damage agents such as ionizing irradiation and chemical agent cisplatin, ATM kinase is activated, leading to a cascade of kinase reactions regulating cell cycle, apoptosis, and DNA damage repair [ 14 15 ] . Many downstream target molecules of ATM kinase were so far identified.

  • TNFα elevates ceramide in CLENDO cells, whereas sFasL elevates ceramide in primary luteal steroidogenic cells [ 26 ] . Ceramide treatment induces apoptosis in both cell types, suggesting that the sphingomyelin pathway may be a common mediator of cell death among distinct cell types within the CL.


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