Words similar to apoptotic
Example sentences for: apoptotic
How can you use “apoptotic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Cells were identified as apoptotic only when they were doubly labeled (Figure 6).
Apoptotic nuclei were detected using DAPI staining (1 μg/ml; 10 min) in cell cultures fixed with 4% paraformaldehyde, and analyzed via fluorescence microscopy to assess chromatin condensation and segregation.
24 cells and primary mouse hepatocytes, through activation of the Fas receptor in a FasL-independent manner [ 19 25 ] . Moreover, GCDCA was demonstrated to activate both initiator and effector caspases, and that the apoptotic response can be blocked by Crm A, a caspase 8 inhibitor [ 25 ] . The mechanism by which bile acids stimulate the activation of Fas receptor remains unclear.
have demonstrated that spontaneously hypertensive rats(SHR) with symptoms of heart failure had significantly higher levels ofapoptotic myocytes than control myocytes [ 37 ] .When treated with an angiotensin-converting enzyme inhibitor, thenumber of apoptotic cells in the SHR with symptoms of heart failurewas dramatically reduced to control levels; controls were SHR withoutsymptoms of heart failure [ 37 ] . Kajstura et al.have also reported that angiotensin II increased the percentageof apoptotic cells in isolated adult rat ventricular myocytes, andthis effect was mediated by AT-1 receptors [ 38 ] .Although ventricular function was not assessed in these studies,the observations raise the possibility that, like our findings withcarvedilol, the beneficial effect of ACE-inhibitors or AT-1 receptorblockers in heart failure may in part be attributed to an inhibitionof myocyte apoptosis with a resultant improvement in in vivo cardiacfunction, a concept that needs further study.
Analysis within each population reveals that, in control mice, 2.47 ± 0.65% of 2C, 0.32 ± 0.23% of S-phase, 2.26 ± 0.76% of 4C, and 0.44 ± 0.40% of 1C cells were apoptotic.
Loading...