Example sentences for: apoptotic

How can you use “apoptotic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Apoptotic nuclei were detected using DAPI staining (1 μg/ml; 10 min) in cell cultures fixed with 4% paraformaldehyde, and analyzed via fluorescence microscopy to assess chromatin condensation and segregation.

  • Under these conditions apoptosis may result from the production of cytokines [ 1 ] , cell activation [ 2 3 4 ] , infective agents [ 5 ] and adverse responses to pharmaceuticals [ 6 7 ] . Depending on the agonist or eliciting milieu, apoptotic cell death is accompanied by the activation of various cell death pathways including caspases, ceramide, altered gene expression, mitochondrial dysfunction and consumption of ATP e.g., with DNA repair, that result in histone-associated DNA fragmentation [ 8 9 ] . Many of these cell death pathways are also associated with the secondary production of oxidants [ 10 ] which appears to contribute to the magnitude of cell death.

  • In a study of expression of CD59 and CD105 on endothelial cells, apoptotic bodies and other cell fragments, the confluent HUVEC at 48 hrs in culture were treated for 24 hrs with 0.5% DMSO, 500 nM or 5 μM CPT in medium.

  • The proportion of early apoptotic cells in lines A, B, and wild-type was determined by flow cytometry in the presence of propidium iodide and annexin V-FITC [ 25, 54, 55].

  • The nature of the 185delAG frameshift makes it difficult to determine if the apoptotic alterations seen are directly caused by the mutation or by downstream effects of it and certainly deserves further scrutiny.


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