Words similar to antimuscarinic
Example sentences for: antimuscarinic
How can you use “antimuscarinic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Olanzapine therapy is associated with a number of side effects, including somnolence, agitation, nervousness, headaches, dizziness, weight gain, constipation and dry mouth [ 5 ] . Olanzapine, however, does not produce extrapyramidal side effects, postural hypotension or hemotoxicity (a particular problem for patients on clozapine therapy [ 13 ] ). Although urinary retention as a result of olanzapine therapy may be predicted from binding studies due to olanzapine's antimuscarinic activity [ 12 ] only 1 case report of micturition disturbance associated with olanzapine has recently appeared [ 14 ] . On the other hand, several reports of urinary disturbances due to clozapine can be found in the clinical literature [ 3 10 15 ] .
It is tempting to propose that the greater effect of olanzapine on the EUS may be due to its antimuscarinic activity, which risperidone does not have.
Risperidone provides an interesting comparison to olanzapine since it has a similar pharmacological profile to olanzapine but without the antimuscarinic activity.
A direct inhibitory action of olanzapine on the EUS muscle itself is not expected and was not seen with clozapine [ 7 ] . However, antimuscarinic effects alone cannot account for all of the effects of olanzapine on the EUS, since risperidone had a similar effect although not quite as pronounced and risperidone has little or no affinity for muscarinic receptors [ 16 ] . Therefore, antagonism of other transmitter systems, e.g.
6 ng/ml plasma concentration [ 22 23 24 ] ) is greater than the first dose observed to produce significant peripheral antimuscarinic effects in this study (1.
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