Words similar to antimuscarinic
Example sentences for: antimuscarinic
How can you use “antimuscarinic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Olanzapine therapy is associated with a number of side effects, including somnolence, agitation, nervousness, headaches, dizziness, weight gain, constipation and dry mouth [ 5 ] . Olanzapine, however, does not produce extrapyramidal side effects, postural hypotension or hemotoxicity (a particular problem for patients on clozapine therapy [ 13 ] ). Although urinary retention as a result of olanzapine therapy may be predicted from binding studies due to olanzapine's antimuscarinic activity [ 12 ] only 1 case report of micturition disturbance associated with olanzapine has recently appeared [ 14 ] . On the other hand, several reports of urinary disturbances due to clozapine can be found in the clinical literature [ 3 10 15 ] .
A direct inhibitory action of olanzapine on the EUS muscle itself is not expected and was not seen with clozapine [ 7 ] . However, antimuscarinic effects alone cannot account for all of the effects of olanzapine on the EUS, since risperidone had a similar effect although not quite as pronounced and risperidone has little or no affinity for muscarinic receptors [ 16 ] . Therefore, antagonism of other transmitter systems, e.g.
Therefore, although olanzapine had a peripheral effect on bladder contraction amplitude, as might be expected from its antimuscarinic effects, this effect is not reflected in the peak contraction pressures observed during cystometry.
Risperidone provides an interesting comparison to olanzapine since it has a similar pharmacological profile to olanzapine but without the antimuscarinic activity.
We tested for peripheral antimuscarinic actions of both neuroleptics by examining their effects on bladder contractions elicited by electrical stimulation of the pelvic nerve.
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