Example sentences for: antimuscarinic

How can you use “antimuscarinic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Finally, possible side effects of neuroleptics, such as urinary retention, may be predicted from binding studies using human brain tissue [ 12 ] if antimuscarinic affinities will correspond to antimuscarinic effects on the bladder.

  • We tested for peripheral antimuscarinic actions of both neuroleptics by examining their effects on bladder contractions elicited by electrical stimulation of the pelvic nerve.

  • Therefore, although olanzapine had a peripheral effect on bladder contraction amplitude, as might be expected from its antimuscarinic effects, this effect is not reflected in the peak contraction pressures observed during cystometry.

  • Risperidone provides an interesting comparison to olanzapine since it has a similar pharmacological profile to olanzapine but without the antimuscarinic activity.

  • Olanzapine therapy is associated with a number of side effects, including somnolence, agitation, nervousness, headaches, dizziness, weight gain, constipation and dry mouth [ 5 ] . Olanzapine, however, does not produce extrapyramidal side effects, postural hypotension or hemotoxicity (a particular problem for patients on clozapine therapy [ 13 ] ). Although urinary retention as a result of olanzapine therapy may be predicted from binding studies due to olanzapine's antimuscarinic activity [ 12 ] only 1 case report of micturition disturbance associated with olanzapine has recently appeared [ 14 ] . On the other hand, several reports of urinary disturbances due to clozapine can be found in the clinical literature [ 3 10 15 ] .


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