Words similar to antigen-specific
Example sentences for: antigen-specific
How can you use “antigen-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:
Another study suggested that liver endothelial cells can induce antigen-specific tolerance of CD8 +T cells [ 51 ] . Perhaps RIP-Tag tumor endothelium develops a similar capability to induce tolerance to extravasating CD4 +T cells, a capability disrupted by radiation.
First, sub-lethal radiation may reduce antigen-specific immune tolerance mediated by bone marrow-derived cells, including regulatory T cells, in the tumor-draining lymph nodes.
Antigen-specific T cells encounter antigen presented by dendritic cells that migrate to the paracortical regions of draining lymph nodes after initial antigen contact [ 1 ] . Only dendritic cells have the capacity to induce activation in resting peripheral T cells [ 2 3 ] . Once activated, differentiated T helper cells contact antigen-specific B cells and provide signals for B cell differentiation via CD154-CD40 interactions, as well as by the production of cytokines [ 4 5 6 ] . Consistent with this general understanding of the induction of antibody responses to protein immunogens, good antibody responses to synthetic peptide-epitope constructs have been shown to depend on the presence, orientation, and multiplicity of the T cell epitope in the construct [ 7 8 9 10 11 ] . As a confirmation of this finding with synthetic epitope constructs, most protein immunogens studied to date contain multiple T cell epitopes, for example [ 12 13 ] .
Serum samples were tested for antigen-specific IgG antibodies by ELISA.
In addition, the careful analysis of antigen-specific T cell clones, such as that reported here by Lee and colleagues, will be crucial to ascertain the quality of the elicited immune response.
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