Example sentences for: antigen-specific

How can you use “antigen-specific” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 10 TCR Tg mice, we have generated an antigen-specific model with which to study the effects of adenovirally delivered genes on T cell activation and differentiation.

  • High affinity humoral immune responses to most protein antigens require cognate interactions between antigen-specific T and B cells.

  • Previous studies have shown that adoptively transferred tumor antigen-specific CD4 +T cells can be tolerized in the secondary lymphoid organs [ 9 34 ] , including the RIP-Tag2 model [ 30 ] . Radiation may kill or disable regulatory T cells [ 35 36 ] , or other bone marrow-derived tolerizing cells and prevent the induction of tolerance in adoptively transferred tumor-specific T cells [ 9 ] . Additionally, the high but sub-lethal dose of radiation used leads to significant lymphopenia [ 37 ] . The sudden reduction in lymphocyte number may create the spatial allowance in spleen and lymph nodes necessary for the homing, activation and expansion of he adoptively-transferred T cells.

  • In addition, the careful analysis of antigen-specific T cell clones, such as that reported here by Lee and colleagues, will be crucial to ascertain the quality of the elicited immune response.

  • Therefore, because of the risk of induction of anaphylactic sensitization, extreme caution needs to be used in developing any type of antigen-specific immunosuppressive therapy for the prevention or treatment of T1DM.


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