Example sentences for: antigen-presenting

How can you use “antigen-presenting” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Consequently, heteroclitic peptide analogs are predicted to be more immunogenic than their native counterparts because of more stable binding at the surface of antigen-presenting cells (APCs).

  • These differentiated cells, although usually stable, sometime exhibit proliferative activity and increase in many cutaneous immune response states [ 23 39 40 ] . The inability of PTU to reduce CD1a expression in biopsy samples of patients with psoriasis suggests that the mechanism of action of this drug is psoriasis is not due to any effect on skin antigen-presenting cells or production of IL-12, a motive cytokine that is responsible for initiation and maintenance of the cytokine stimulatory cascade that leads to formation of the psoriatic plaque [ 16 ] . In support of this argument is the fact that circulating IL-12 did not show any significant change with PTU treatment (submitted).

  • In practical terms, these results suggest that systemic IL-2 administration may facilitate T-cell effector function in the target organ not by sustaining their proliferation, as presently believed, but rather by promoting their migration and by providing a milieu conducive to their activation in situ through activation of antigen-presenting cells.

  • For some experiments, the transduced cells were then activated with 5 μM ionomycin and 50 ng/ml PMA for 4 h or stimulated for 18 h by immobilized anti-CD3 (pre-coated at 10 μg/ml in PBS) or 5 μg/ml OVA peptide with antigen-presenting cells before analysis.

  • A key element in the generation of the cytokine signals responsible for formation of a psoriatic plaque is the skin antigen-presenting cell or Langerhans cell.


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