Example sentences for: antigen-presenting

How can you use “antigen-presenting” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • B7-1) on tumor cells [ 45 ] . Radiation has been shown to increase the expression of MHC class I and II molecules in tumor cell lines [ 46 47 ] . Thus, the tissue damage signals evoked by ionizing radiation may trigger the activation and infiltration of antigen-presenting cells, in particular dendritic cells [ 38 48 49 50 ] . Indeed, in the regression study, we observe some increase of tumor-infiltrating dendritic cells in the group receiving the single radiation treatment.

  • A key element in the generation of the cytokine signals responsible for formation of a psoriatic plaque is the skin antigen-presenting cell or Langerhans cell.

  • Consequently, heteroclitic peptide analogs are predicted to be more immunogenic than their native counterparts because of more stable binding at the surface of antigen-presenting cells (APCs).

  • Skin antigen-presenting cells (Langerhans cells) appear to play an important role in the initiating events that lead to the cytokine cascade that results in keratinocyte proliferation and development of psoriatic lesions [ 16 17 18 ] . Effective therapeutic approaches to psoriasis treatment, such as psoralen UV-A therapy (PUVA), which result in depletion of APCs in the skin [ 19 20 ] , and UV-B [ 21 ] , lead to one of the most sustained improvement in psoriasis.

  • An additional concern was that IFN-γ-producing effector cells might inhibit potential IL-4 precursors from differentiating or expanding in these cultures, although previous studies [ 29, 30, 31] demonstrated that IFN-γ indirectly affected the generation of IL-4-secreting cells through the activities of antigen-presenting cells.


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