Words similar to antigen-presenting
Example sentences for: antigen-presenting
How can you use “antigen-presenting” in a sentence? Here are some example sentences to help you improve your vocabulary:
CD4 +CD25 +T cells (1 × 10 4) isolated from naïve BALB/c mice were mixed with CD4 +CD25 -T cells (5 × 10 4) from arthritic mice in the presence of irradiated syngenic splenocytes as antigen-presenting cells (7.
Methodologies described in this report were tested on a list of 70 genes (see Additional data files) derived from a subset of conditions belonging to a sample gene-expression dataset generated to study the transcriptional response of professional antigen-presenting cells to pathogens using high-density oligonucleotide arrays (D.
These differentiated cells, although usually stable, sometime exhibit proliferative activity and increase in many cutaneous immune response states [ 23 39 40 ] . The inability of PTU to reduce CD1a expression in biopsy samples of patients with psoriasis suggests that the mechanism of action of this drug is psoriasis is not due to any effect on skin antigen-presenting cells or production of IL-12, a motive cytokine that is responsible for initiation and maintenance of the cytokine stimulatory cascade that leads to formation of the psoriatic plaque [ 16 ] . In support of this argument is the fact that circulating IL-12 did not show any significant change with PTU treatment (submitted).
IL-10, a cytokine produced by activated macrophages and Th2-type T cells, has crucial inhibitory effect against several Th-1 type immune responses, such as the antigen-presenting functions of monocytes and macrophages [ 52 53 ] . IL-10 may play an important role in preventing the induction of IBD, since animals deficient in IL-10 will develop colitis spontaneously, and low levels of IL-10 are positively correlated with recurrences of Crohn's disease [ 25 54 ] . However, unlike TNF-α based therapies, the administration of recombinant IL-10 (rIL-10) shows poor clinical efficacy.
An additional concern was that IFN-γ-producing effector cells might inhibit potential IL-4 precursors from differentiating or expanding in these cultures, although previous studies [ 29, 30, 31] demonstrated that IFN-γ indirectly affected the generation of IL-4-secreting cells through the activities of antigen-presenting cells.
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