Words similar to antigen-presenting
Example sentences for: antigen-presenting
How can you use “antigen-presenting” in a sentence? Here are some example sentences to help you improve your vocabulary:
Consequently, heteroclitic peptide analogs are predicted to be more immunogenic than their native counterparts because of more stable binding at the surface of antigen-presenting cells (APCs).
Changing the interaction of peptide, MHC class II molecules, T cell receptors and other antigen-presenting cell specific ligand interactions to foster stronger, higher affinity T cell signalling has been shown in mice to skew T cell differentiation from Th2 to Th1-like patterns [ 40 41 42 43 44 45 46 47 48 49 50 ] . Differences in Th-differentiation patterns have downstream effects on the type of immune response mounted, and in particular on the isotypes of antibody expressed.
The results of this study suggest that IL-2 administration induces inflammation at the tumor site, with three predominant secondary effects: activation of antigen-presenting monocytes; a massive production of chemoattractants that may recruit other immune cells to the tumor site, among which are the chemokines MIG and PARC specific for T cells; and the activation of lytic mechanisms ascribable to monocytes (calgranulin, grancalcin) and NK cells (for example, NKG5, NK4) (Figure 8).
IL-10, a cytokine produced by activated macrophages and Th2-type T cells, has crucial inhibitory effect against several Th-1 type immune responses, such as the antigen-presenting functions of monocytes and macrophages [ 52 53 ] . IL-10 may play an important role in preventing the induction of IBD, since animals deficient in IL-10 will develop colitis spontaneously, and low levels of IL-10 are positively correlated with recurrences of Crohn's disease [ 25 54 ] . However, unlike TNF-α based therapies, the administration of recombinant IL-10 (rIL-10) shows poor clinical efficacy.
B7-1) on tumor cells [ 45 ] . Radiation has been shown to increase the expression of MHC class I and II molecules in tumor cell lines [ 46 47 ] . Thus, the tissue damage signals evoked by ionizing radiation may trigger the activation and infiltration of antigen-presenting cells, in particular dendritic cells [ 38 48 49 50 ] . Indeed, in the regression study, we observe some increase of tumor-infiltrating dendritic cells in the group receiving the single radiation treatment.
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