Words similar to antigen-induced
Example sentences for: antigen-induced
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We have also investigated whether mactinin is present in the antigen-induced arthritis model in rabbits [ 13 14 ] . Macrophages are believed to be important in this model of rheumatoid arthritis [ 15 16 ] , and both the arthritic and control joint fluid can be tested for mactinin.
However, mactinin was not present in the control joint fluid in the rabbit antigen-induced arthritis model, suggesting that mactinin is specific for the inflammation process.
To establish antigen-induced arthritis (AIA), rabbits were sensitized to ovalbumin by intradermal injections of 5 mg ovalbumin emulsified in Freund's complete adjuvant.
The overall effect of urokinase in the antigen-induced arthritis model seems to be beneficial, because chronic joint inflammation and bone erosion are significantly worse in urokinase-deficient mice [ 30 ] . However, the ability of urokinase-generated mactinin to enhance proteolysis might be deleterious.
Similarly, administration of v-IL-10 into one knee of rabbits with antigen-induced arthritis was able to confer a therapeutic effect in the contralateral untreated knee.