Words similar to antigens
Example sentences for: antigens
How can you use “antigens” in a sentence? Here are some example sentences to help you improve your vocabulary:
Interestingly, CD14 and TLR2, receptors involved in innate immune recognition of microbial antigens, were both induced.
First, defective tolerance from skewed X inactivation should only be directed at X-linked antigens that are polymorphic, and for which the individual is heterozygous.
In a study by Lee and colleagues in this issue of PLoS Medicine [9], despite the careful study design, vaccination with these peptides resulted in the recruitment of T cells that bound antigens less efficiently and had lower tumor reactivity than those from the endogenous response to the tumor.
Although MHCII are not expressed by the vast majority of studied mouse and human tumors, CD4+ T lymphocytes specific to MHCII-restricted tumor antigens have been found in various cancers [ 1 ] . Those lymphocytes are believed to be generated in vivo following the recognition of MHCII-tumor peptide complexes expressed by host antigen presenting cells and can cause regression of MHCII-negative tumors indirectly, via secretion of cytokines such as IL-2 or IFNg [ 2 ] . The released cytokines can recruit and activate cytotoxic CD8+ T lymphocytes and/or accessory cells (eosinophills, macrophages) which further mediate tumor destruction.
However, when T cells reactive against tumor antigens are expanded ex vivo and then transferred back into tumor-bearing hosts, results have been mixed in treating both melanoma [ 2 3 4 ] and lymphoma [ 5 6 7 ] . Several explanations for these variable results have been suggested by studies of T cell immunity in mice, involving experimental tumors derived from inoculation of cell lines.
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