Words similar to anneals
Example sentences for: anneals
How can you use “anneals” in a sentence? Here are some example sentences to help you improve your vocabulary:
Recently a new method for SNP detection from genomic DNA based on DNA ligase-mediated single nucleotide discrimination and signal amplification by Rolling Circle Amplification (RCA) has been described [ 6 7 8 9 10 ] . An oligonucleotide Open Circle Probe (OCP) anneals to the target SNP such that the 5' and 3' ends of the OCP can be ligated together forming a circle topologically linked to the target.
The primary amplification primer sequences are present in the OCP backbone, not in the portion of the OCP that anneals to target, allowing optimized P1 and P2 pairs, to be used for many different targets.
The T m of the 5' OCP arm is greater than the reaction temperature and so the OCP tightly anneals to the target.