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Example sentences for: analogs

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At this concentration tetramethylrhodamine-SP inhibited I M by 57 ± 33 %, (n = 4), however Alexa 488-SP did not inhibit I M . Dose-response curves for the analogs that inhibited I M and for unlabeled SP are shown in the plots in Fig.
While Lerisetron contains no carbonyl group, the second nitrogen contained in the benzimidazole heterocycle could act as bioisostere of this functional group [ 22 ] . Orjales demonstrated the importance of the N-benzyl group by synthesizing several N1 substituted analogs of Lerisetron.
These four analogs only produced Ca ++responses in cells transfected with the SPR; they had no effect in non-transfected cells.
Two-way analysis of variance followed by Student-Newman-Keuls test showed that there was a dose-dependent effect (p < 0.001) on the binding of unlabeled SP and the SP analogs to the rSPR.
Modified ribo- and deoxyribonucleoside analogs have been used in a variety of applications [ 12 13 14 ] , but their use has been limited in the field of microarrays [ 23 ] . We demonstrate that 2-aminoadenosine or 2,6-diaminopurine (DAP), an analog of adenosine, significantly increases signal intensity for a wide range of probe sequences, whereas C-5 methylated pyrimidine analogs of cytosine and uridine decreased signal intensities across the entire range of probe sequences on our platform (Figure 2).