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Example sentences for: analogs
How can you use “analogs” in a sentence? Here are some example sentences to help you improve your vocabulary:
The middle histidine of the histidine triad (His96 in human Fhit), which is critical for hydrolysis of ApppA by Fhit [ 14 16 ] , is not necessary for tumor suppression [ 17 18 ] . Nonetheless, wild-type and His96Asn forms of Fhit are saturated by ApppA in the low micromolar range and form stable complexes with non-hydrolyzable ApppA in which two ApppA analogs are bound per Fhit dimer and all phosphates cluster on one surface of the protein [ 16 ] . These observations suggested that Fhit-substrate complexes may be the active, signaling form of Fhit and that the function of the catalytically essential histidine may be to terminate the lifetime of signaling complexes [ 16 ] .
Treatment of animals with PGF 2α or its analogs results in endothelial cell death in vivo [ 43 ] , suggesting that PGF 2α may have a direct effect on CLENDO cells.
Because phosphorothioate analogs of 5 and 6 were better inhibitors than the corresponding phosphates, phosphorodithioate analog 6c was prepared together with five additional compounds as phosphates and phosphorothioates.
The evidence presented here suggests that four of the analogs, BODIPY Fl-SP, fluorescein-SP, Oregon Green 488-SP and tetramethylrhodamine-SP, are acting specifically at the SPR.
The effects of these mutations on the K i for analogs 1 and 2 are shown in figure 4B, 4Cand Table 1. Analog 1 inhibited [ 3H]-granisetron binding to W89F receptors with a K i of 170 ± 54 nM (7 ± 3.2 fold increase, p < 0.001) and W89Y receptors with a K i of 81 ± 14 nM (3.
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