Words similar to analgesic
Example sentences for: analgesic
How can you use “analgesic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Our data clearly show that nalbuphine is a potent agonist at the μ opioid receptor with an efficacy similar to that of morphine, thus agreeing with in vivo data showing that morphine and nalbuphine are equally potent as analgesics [ 33 ] . However, other reports have described nalbuphine as a "mixed agonist/antagonist" with agonism at κ opioid receptors and antagonism at μ opioid receptors based on in vivo data [ 11 33 ] . This categorization is likely due to the fact that nalbuphine has been shown to reduce the ventilatory depressant effect of other opioids, while adding to their analgesic effect [ 33 ] . Nalbuphine is also used clinically to reduce the opioid-mediated side effects such as itching, without completely reversing the analgesic effects of the full agonists [ 34 35 36 ] . According to our data, although nalbuphine is clearly a potent agonist at μ receptors, its levels of agonism is significantly lower than the very efficacious drug fentanyl and the endogenous ligand β-endorphin.
Meanwhile, nicotine is also being investigated as an analgesic in humans.
Some topically administered therapies, such as lidocaine and capsaicin, were associated with analgesic efficacy in selected patients.
However, they found evidence for analgesic efficacy in established PHN for orally administered therapies, such as tricyclic antidepressants, some opioids, gabapentin, tramadol, and pregabalin.
Exposure misclassification may also have affected our results, as we based our analyses on self-reported analgesic use and were not able to independently verify this information.
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